Atropine
- Generic Name
- Atropine
- Brand Names
- Atnaa, Atropen, Busulfex, Donnatal, Duodote, Enlon-plus, Isopto Atropine, Lomotil, Minims Atropine Sulphate, Motofen, Phenohytro
- Drug Type
- Small Molecule
- Chemical Formula
- C17H23NO3
- CAS Number
- 51-55-8
- Unique Ingredient Identifier
- 7C0697DR9I
- Background
Atropine is an alkaloid originally synthesized from Atropa belladonna. It is a racemic mixture of d-and l-hyoscyamine, of which only l-hyoscyamine is pharmacologically active. Atropine is generally available as a sulfate salt and can be administered by intravenous, subcutaneous, intramuscular, intraosseous, endotracheal and ophthalmic methods. Oral atropine ...
- Indication
The intravenous, intramuscular, subcutaneous, intraosseous and endotracheal use of atropine is indicated for the temporary blockade of severe or life-threatening muscarinic effects. The intramuscular use of atropine in the form of a pen injector is indicated for the treatment of poisoning by susceptible organophosphorus nerve agents having cholinesterase act...
- Associated Conditions
- Amblyopia, Atrioventricular Heart-block, Bradycardia, Bronchospasm, Crying, Detrusor Hyperreflexia, Excessive bronchial secretion, Hypertonic uterine contraction, Hypertonicity of the small intestine, Ocular Inflammation, Parkinsonism, Peptic Ulcer, Poisoning by parasympathomimetics (cholinergics), Poisoning caused by mushrooms, Poisoning caused by organophosphate anticholinesterase nerve agents, Poisoning caused by organophosphorus pesticides, Pylorospasm, Rhinorrhoea, Sinus Bradycardia, Spasms, Toxic effect of organophosphate and carbamate, Hypermobility of the colon, Laughing, Life-threatening muscarinic side effects, Muscarinic side effects, Severe muscarinic side effects
- Associated Therapies
- -
Low Concentration Atropine for Myopia Progression in School Children
- First Posted Date
- 2014-05-05
- Last Posted Date
- 2018-01-30
- Lead Sponsor
- Chang Gung Memorial Hospital
- Target Recruit Count
- 60
- Registration Number
- NCT02130167
- Locations
- 🇨🇳
Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan
the Effect of Low-Concentration Atropine Combined With Auricular Acupoint Stimulation in Myopia Control
- Conditions
- Interventions
- First Posted Date
- 2014-02-05
- Last Posted Date
- 2014-02-05
- Target Recruit Count
- 73
- Registration Number
- NCT02055378
- Locations
- 🇨🇳
Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taipei, New Taipei City, Taiwan
Atropine-effect During Propofol/Remifentanil Induction
- Conditions
- Interventions
- First Posted Date
- 2013-06-07
- Last Posted Date
- 2024-04-17
- Lead Sponsor
- University Medical Center Groningen
- Target Recruit Count
- 60
- Registration Number
- NCT01871922
- Locations
- 🇳🇱
University Medical Center Groningen, Groningen, Netherlands
Intrathecal Levobupivacaine With Opioids for Caesarean Section
- First Posted Date
- 2013-05-21
- Last Posted Date
- 2013-05-21
- Lead Sponsor
- Baskent University
- Target Recruit Count
- 93
- Registration Number
- NCT01858090
- Locations
- 🇹🇷
Baskent University School of Medicine Adana Teaching and Research Hospital, Adana, Turkey
Olfactory Deficits in MCI as Predictor of Improved Cognition on Donepezil
- First Posted Date
- 2013-05-03
- Last Posted Date
- 2018-07-09
- Lead Sponsor
- New York State Psychiatric Institute
- Target Recruit Count
- 41
- Registration Number
- NCT01845636
- Locations
- 🇺🇸
New York State Psychiatric Institute, New York, New York, United States
Heart Rate Response to Atropine Doses Less Than 0.1mg IV to Anesthetized Infants
- First Posted Date
- 2013-03-27
- Last Posted Date
- 2023-04-06
- Lead Sponsor
- State University of New York at Buffalo
- Target Recruit Count
- 60
- Registration Number
- NCT01819064
- Locations
- 🇺🇸
Women and Children's Hospital of Buffalo, Buffalo, New York, United States
Atropine Versus no Atropine for Neonatal Rapid Sequence Intubation
- First Posted Date
- 2012-05-10
- Last Posted Date
- 2013-09-24
- Lead Sponsor
- University of Manitoba
- Target Recruit Count
- 70
- Registration Number
- NCT01595399
- Locations
- 🇨🇦
Health Sciences Centre, Winnipeg, Manitoba, Canada
Atropin and Glucose Stimulated Insulinsecretion and the Cephalic Insulin Response
- First Posted Date
- 2012-02-16
- Last Posted Date
- 2012-12-07
- Lead Sponsor
- University Hospital, Gentofte, Copenhagen
- Target Recruit Count
- 10
- Registration Number
- NCT01534442
- Locations
- 🇩🇰
Diabetes research Division, Department of Internal Medicin, Gentofte Hospital, Hellerup, Denmark
🇩🇰Diabetes Research Division, Department of Internal Medicine, Gentofte Hospital, Copenhagen Denmark, Hellerup, Denmark
Intubation Time With Low Dose Rocuronium
- Conditions
- Interventions
- First Posted Date
- 2011-11-03
- Last Posted Date
- 2011-11-03
- Lead Sponsor
- Gachon University Gil Medical Center
- Target Recruit Count
- 44
- Registration Number
- NCT01464489
- Locations
- 🇰🇷
Gachon University Gil Medical Center, Incheon, Korea, Republic of
Role of Neural and Hormonal Regulation Factors on Insulin Secretion After Gastric Bypass Surgery
- Conditions
- Interventions
- First Posted Date
- 2009-10-09
- Last Posted Date
- 2024-08-28
- Target Recruit Count
- 160
- Registration Number
- NCT00992901
- Locations
- 🇺🇸
Texas Diabetes Institute - University Health System, San Antonio, Texas, United States
🇺🇸South Texas Veterans Health Care System, San Antonio, Texas, United States
Drug Development Updates
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