Modufolin
- Generic Name
- Modufolin
- Drug Type
- Small Molecule
- Chemical Formula
- C20H23N7O6
- CAS Number
- 31690-11-6
- Unique Ingredient Identifier
- Z8R4A37V9Q
- Background
Modufolin is under investigation for the treatment of Osteosarcoma.
Modelle 001, TS-inhibition in Colorectal Liver Metastases Comparing Arfolitixorin and Calciumfolinate
- First Posted Date
- 2019-10-15
- Last Posted Date
- 2020-08-27
- Lead Sponsor
- Vastra Gotaland Region
- Target Recruit Count
- 30
- Registration Number
- NCT04126655
- Locations
- 🇸🇪
Sahlgrenska University Hospital, Gothenburg, Sweden
A Study to Compare the Efficacy of Arfolitixorin Versus Leucovorin in Combination With 5 Fluorouracil, Oxaliplatin, and Bevacizumab in Patients With Advanced Colorectal Cancer
- First Posted Date
- 2018-11-23
- Last Posted Date
- 2023-10-26
- Lead Sponsor
- Isofol Medical AB
- Target Recruit Count
- 490
- Registration Number
- NCT03750786
- Locations
- 🇺🇸
840-01 - HOAG Memorial Hospital, Newport Beach, California, United States
🇨🇦124-11 - CISSS de Chaudière-Appalaches, Lévis, Quebec, Canada
🇫🇷250-05 - Clinique Sainte Anne, Strasbourg, France
Study Evaluating ECG Effects, Safety, Tolerability and Pharmacokinetics of Single Doses of Modufolin (Arfolitixorin) in Healthy Volunteers Tetrahydrofolate in Healthy Male Volunteers
Phase 1
Completed
- Conditions
- Phase I Study in Healthy Volunteers to Evaluate ECG Effect
- Interventions
- First Posted Date
- 2017-06-29
- Last Posted Date
- 2020-09-25
- Lead Sponsor
- Isofol Medical AB
- Target Recruit Count
- 33
- Registration Number
- NCT03203564
- Locations
- 🇸🇪
CTC Clinical Trial Consultants, Uppsala, Sweden
Modufolin (Arfolitixorin) in Combination With 5-Fluorouracil Alone or Together With Oxaliplatin or Irinotecan in Colorectal Cancer
Phase 1
Completed
- Conditions
- Colorectal Neoplasm
- Interventions
- First Posted Date
- 2014-09-19
- Last Posted Date
- 2020-09-09
- Lead Sponsor
- Isofol Medical AB
- Target Recruit Count
- 105
- Registration Number
- NCT02244632
- Locations
- 🇬🇷
251 General Airforce Hospital, Athens, Greece
🇬🇷Metropolitan General Hospital, Athens, Greece
🇳🇴Oslo University Hospital - Radiumhospitalet, Oslo, Norway
PK/PD Investigation of Modufolin (Arfolitixorin) in Plasma, Tumor and Adjacent Mucosa Adjacent Mucosa in Patients With Colon Cancer
Phase 1
Completed
- Conditions
- Colonic Neoplasms
- Interventions
- First Posted Date
- 2012-09-10
- Last Posted Date
- 2020-09-25
- Lead Sponsor
- Isofol Medical AB
- Target Recruit Count
- 32
- Registration Number
- NCT01681472
- Locations
- 🇸🇪
Sahlgrenska University Hospital, Gothenburg, Sweden
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