Calcium carbonate

Generic Name: Calcium carbonate

Brand Names: Alka-seltzer Fruit Chews, Alka-seltzer Heartburn Plus Gas Relief, Alkums, Bayer Womens, Cal Gest, Chooz, Diphen, Duo Fusion, Healthy Mama, Irospan 24/6 Kit, Magnebind 400 Rx, Meijer, Mi-acid Double Strength, Mylanta Tonight, Nutralox, Pepcid Complete, Pepto-bismol, Phazyme, Pregvit, Rolaids Advanced, Rolaids Reformulated Aug 2006, Rolaids Ultra Strength, Titralac, Titralac Plus, Tums

Drug Type: Small Molecule

Chemical Formula: CCaO_₃

CAS Number: 471-34-1

Unique Ingredient Identifier: H0G9379FGK

Background: Calcium carbonate is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. Calcium carbonate may also be used as a nutritional supplem...

Indication: For relief of heartburn and acid indigestion. May also be used as a nutritional supplement or to treat hypocalcemia.

Associated Conditions: Bloating, Calcium Deficiency, Calcium Metabolism Disorders, Calcium and Vitamin D Deficiencies, Colic, Dyspepsia, Gastric Ulcer, Gastroesophageal Reflux, Haemorrhoids, Heartburn, Hot Flashes, Hyperacidity, Hyperphosphataemia, Low Bone Density, Osteodystrophy, Osteomalacia, Osteoporosis, Post Operative Gas, Postmenopausal Osteoporosis, Proctitis, Reflux Acid, Rickets, Vertebral Fractures, Calcium loss, Gastrointestinal ulceration

Associated Therapies: Dietary supplementation

Clinical Trials

A Study to Assess the Pharmacokinetics of Lanthanum Carbonate, Investigate and Compare the Efficacy, Safety and Tolerability of Lanthanum Carbonate With Calcium Carbonate in Hyperphosphataemic Children and Adolescents With Chronic Kidney Disease on Dialysis

Phase 2

Completed

Conditions: Chronic Kidney Disease
Hyperphosphatemia

Interventions: Drug: Lanthanum Carbonate
Drug: Calcium Carbonate

First Posted Date: 2012-10-01

Last Posted Date: 2021-06-10

Lead Sponsor: Shire

Target Recruit Count: 63

Registration Number: NCT01696279

Locations: 🇭🇺
Szegedi Tudomanyegyetem Altalanos Orvostudomanyi Kar, Szeged, Hungary
🇨🇿
Fakultni nemocnice Ostrava, Ostrava, Czechia
🇩🇪
Medizinische Hochschule Hannover, Hannover, Germany

and more 19 locations

Role of Calcium And Vitamin D In Nutritional Rickets And It's Management

Phase 4

Completed

Conditions: Nutritional Rickets

Interventions: Drug: Vitamin D and Calcium
Drug: Calcium Carbonate
Drug: Vitamin D

First Posted Date: 2012-04-17

Last Posted Date: 2012-04-19

Lead Sponsor: Lady Hardinge Medical College

Target Recruit Count: 67

Registration Number: NCT01578434

Outcome Study of Lanthanum Carbonate Compared With Calcium Carbonate in Hemodialysis Patients : Landmark Study

Phase 3

Completed

Conditions: Hemodialysis
Hyperphosphatemia

Interventions: Drug: Lanthanum Carbonate
Drug: Calcium Carbonate

First Posted Date: 2012-04-16

Last Posted Date: 2020-11-30

Lead Sponsor: Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan

Target Recruit Count: 2309

Registration Number: NCT01578200

Locations: 🇯🇵
Showa University, Shinagawa, Tokyo, Japan

Phase III Double-blind Comparative Study of BAY77-1931 (Lanthanum Carbonate) With Calcium Carbonate

Phase 3

Completed

Conditions: Hyperphosphatemia

Interventions: Drug: Lanthanum carbonate (BAY77-1931)
Drug: Calcium carbonate

First Posted Date: 2012-01-23

Last Posted Date: 2012-06-08

Lead Sponsor: Bayer

Target Recruit Count: 259

Registration Number: NCT01514851

The Effects of Sevelamer Carbonate on Diabetic Nephropathy

Phase 2

Completed

Conditions: Diabetic Nephropathy

Interventions: Drug: Sevelamer Carbonate
Drug: calcium carbonate

First Posted Date: 2011-12-15

Last Posted Date: 2014-04-09

Lead Sponsor: Gary Striker

Target Recruit Count: 117

Registration Number: NCT01493050

Locations: 🇺🇸
Beth Israel Medical Center, New York, New York, United States
🇺🇸
Icahn School of Medicine at Mount Sinai, New York, New York, United States

Effect of Calcium + Vitamin D Supplementation on Weight Management in Very-low Calcium Consumers

Phase 4

Completed

Conditions: Obesity
Overweight

Interventions: Drug: Calcium Carbonate
Behavioral: Energy restriction

First Posted Date: 2011-10-06

Last Posted Date: 2012-08-01

Lead Sponsor: Changhai Hospital

Target Recruit Count: 53

Registration Number: NCT01447433

Locations: 🇨🇳
Changhai Hospital, Shanghai, China

High Dose Vitamin D and Calcium for Bone Health in Individuals Initiating HAART

Phase 2

Completed

Conditions: HIV-1 Infection

Interventions: Drug: EFV/FTC/TDF
Drug: Placebo for calcium carbonate
Drug: Calcium Carbonate
Drug: Placebo for vitamin D3
Drug: Vitamin D3

First Posted Date: 2011-07-27

Last Posted Date: 2018-10-12

Lead Sponsor: Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections

Target Recruit Count: 167

Registration Number: NCT01403051

Locations: 🇺🇸
Hosp. of the Univ. of Pennsylvania CRS (6201), Philadelphia, Pennsylvania, United States
🇺🇸
Harbor-UCLA Med. Ctr. CRS (603), Torrance, California, United States
🇺🇸
Stanford CRS (501), Palo Alto, California, United States

and more 36 locations