• A cost-utility analysis in Thailand found that adding SGLT2 inhibitors to standard care for type 2 diabetes patients with heart failure is not cost-effective at current prices.
• The study suggests price reductions of up to 90% for some SGLT2 inhibitors would be needed to meet Thailand's cost-effectiveness threshold.
• The analysis, using national health data, considered direct medical and non-medical costs from a societal perspective, unlike previous studies.
• Canagliflozin showed the lowest incremental cost-effectiveness ratio, but its efficacy data relies on a post-hoc analysis with limited heart failure patients.