Abacavir

Generic Name
Abacavir
Brand Names
Epzicom, Kivexa, Triumeq, Trizivir, Ziagen
Drug Type
Small Molecule
Chemical Formula
C14H18N6O
CAS Number
136470-78-5
Unique Ingredient Identifier
WR2TIP26VS
Background

Abacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclopentene ring. In vivo, abacavir sulfate dissociates to its free base, abacavir.

Indication

Abacavir is indicated in combination with other anti-retroviral agents for the treatment of HIV-1 infection. It is available in a combination product alongside dolutegravir and lamivudine for the treatment of adult and pediatric patients with HIV-1 who weigh ≥10 kg.

Associated Conditions
Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Associated Therapies
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