Pasireotide
- Generic Name
- Pasireotide
- Brand Names
- Signifor
- Drug Type
- Small Molecule
- Chemical Formula
- C58H66N10O9
- CAS Number
- 396091-73-9
- Unique Ingredient Identifier
- 98H1T17066
Overview
Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Background
Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Indication
For the treatment of Cushing’s disease, specifically for those patients whom pituitary surgery has not been curative or is not an option.
Associated Conditions
- Acromegaly
- Cushing's Disease
Clinical Trials
FDA Approved Products
Signifor
Manufacturer:Recordati Rare Diseases, Inc.
Route:SUBCUTANEOUS
Strength:0.6 mg in 1 mL
Approved: 2023/08/03
NDC:55292-132
Signifor
Manufacturer:Recordati Rare Diseases, Inc.
Route:SUBCUTANEOUS
Strength:0.3 mg in 1 mL
Approved: 2023/08/03
NDC:55292-131
Signifor
Manufacturer:Recordati Rare Diseases, Inc.
Route:SUBCUTANEOUS
Strength:0.9 mg in 1 mL
Approved: 2023/08/03
NDC:55292-133
Singapore Approved Products
SIGNIFOR LAR POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION 60MG
Manufacturer:Recordati AG Rare Diseases Branch (manufacture of bulk powder), Sandoz GmbH (primary packager), Abbott Biologicals B.V. (manufacture, primary and secondary packager for solvent), Synergy Health Daniken AG (sterilization site)
Form:INJECTION, POWDER, FOR SUSPENSION
Strength:60mg
Online:Yes
Approved: 2017/02/02
Approval:SIN15170P
SIGNIFOR LAR POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION 40MG
Manufacturer:Novartis Pharma AG (manufacture of bulk powder), Sandoz GmbH (primary packager), Abbott Biologicals B.V. (manufacture, primary and secondary packager for solvent), Synergy Health Daniken AG (sterilization site)
Form:INJECTION, POWDER, FOR SUSPENSION
Strength:40mg
Online:Yes
Approved: 2017/02/02
Approval:SIN15169P
SIGNIFOR LAR POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION 20MG
Manufacturer:Novartis Pharma AG (manufacture bulk powder), Sandoz GmbH (primary packager of powder), Abbott Biologicals B.V. (manufacture, primary and secondary packager for solvent), Synergy Health Daniken AG (sterilization site)
Form:INJECTION, POWDER, FOR SUSPENSION
Strength:20mg
Online:Yes
Approved: 2017/02/02
Approval:SIN15168P
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