Overview
Choline magnesium trisalicylate is a non-acetylated salicylate used widely as a nonsteroidal anti-inflammatory drug. Trisalicylate significantly reduces methotrexate renal clearance, displacing methotrexate from protein, increasing the fraction unbound by 28% .
Background
Choline magnesium trisalicylate is a non-acetylated salicylate used widely as a nonsteroidal anti-inflammatory drug. Trisalicylate significantly reduces methotrexate renal clearance, displacing methotrexate from protein, increasing the fraction unbound by 28% .
Indication
Choline magnesium trisalicylate is used to reduce pain and inflammation caused by conditions such as arthritis. This medication is also used to treat fever in adults.
Associated Conditions
- Fever
- Juvenile Idiopathic Arthritis (JIA)
- Mild pain
- Osteoarthritis (OA)
- Rheumatoid Arthritis
- Acute Shoulder Pain
- Articular inflammation
- Moderate Pain
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2014/05/22 | Phase 2 | Completed | |||
2009/11/09 | Phase 2 | Terminated | |||
2005/09/12 | Phase 1 | Terminated |
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| No FDA approvals found for this drug. | |||||
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No HSA approvals found for this drug. | |||||
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| Choline Magnesium Trisalicylate Tablets | 国药准字H23023060 | 化学药品 | 片剂 | 4/21/2020 | |
| Choline Magnesium Trisalicylate Tablets | 国药准字H22025204 | 化学药品 | 片剂 | 4/13/2021 | |
| Choline Magnesium Trisalicylate Tablets | 国药准字H11021992 | 化学药品 | 片剂 | 12/8/2020 | |
| Choline Magnesium Trisalicylate Tablets | 国药准字H14023310 | 化学药品 | 片剂 | 8/26/2020 | |
| Choline Magnesium Trisalicylate Tablets | 国药准字H20073542 | 化学药品 | 片剂 | 7/23/2020 | |
| Choline Magnesium Trisalicylate Tablets | 国药准字H21022841 | 化学药品 | 片剂 | 5/29/2020 | |
| Choline Magnesium Trisalicylate Tablets | 国药准字H14023778 | 化学药品 | 片剂 | 8/5/2020 | |
| Choline Magnesium Trisalicylate Tablets | 国药准字H41024846 | 化学药品 | 片剂 | 6/17/2020 | |
| Choline Magnesium Trisalicylate Tablets | 国药准字H61022710 | 化学药品 | 片剂 | 1/15/2021 | |
| Choline Magnesium Trisalicylate Tablets | 国药准字H37023530 | 化学药品 | 片剂 | 4/2/2020 |
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| No PPB approvals found for this drug. | |||||
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
|---|---|---|---|---|---|
| No TGA approvals found for this drug. | |||||