Acetaminophen

Generic Name: Acetaminophen

Brand Names: Acephen, Acetadryl, Allzital, Apadaz, Arthriten Inflammatory Pain, Bupap, Butapap, Cetafen, Children's Silapap, Coricidin Hbp Cold & Flu, Darvocet-N, Dayquil Sinex, Diphen, Dolofin, Dologen, Dologesic Reformulated Jun 2016, Duralgina, Dvorah, Endocet, Esgic, Exaprin, Excedrin, Excedrin PM Triple Action, Excedrin Tension Headache, Feverall, Fioricet, Fioricet With Codeine, Goody's Back & Body Pain Relief, Goody's Body Pain, Goody's Extra Strength, Goody's Headache Relief Shot, Goody's PM, Hycet, Legatrin PM, Little Fevers, Lorcet, Lortab, Mapap, Mersyndol, Midol Complete, Midol Cramps & Bodyaches, Nalocet, Norco, Orbivan, Pamprin Max Formula, Pamprin Multi-symptom, Panadol, Pediacare Children's Fever Reducer Pain Reliever, Percocet, Percogesic Reformulated Jan 2011, Pharbetol, Premsyn Pms, Prolate, Rivacocet, Robaxacet, Robaxacet-8, Roxicet, Sudafed PE Sinus Headache, Tactinal, Tencon, Trezix, Triatec, Triatec-30, Triatec-8, Tylenol, Tylenol PM, Tylenol With Codeine, Ultracet, Vanatol, Vanatol S, Vanquish, Xodol, Xolox, Zamicet, Zflex, Zydone

Drug Type: Small Molecule

Chemical Formula: C_₈H_₉NO_₂

CAS Number: 103-90-2

Unique Ingredient Identifier: 362O9ITL9D

Background: Acetaminophen (paracetamol), also commonly known as Tylenol, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). It is also used for its antipyretic effects, helping to reduce fever. This drug was initially approved by the U.S. FDA in 1951 and is available in a var...

Indication: In general, acetaminophen is used for the treatment of mild to moderate pain and reduction of fever. It is available over the counter in various forms, the most common being oral forms.
...

Associated Conditions: Acute Gouty Arthritis, Acute Musculoskeletal Pain, Allergic Reaction, Allergy to Tree Pollen, Ankylosing Spondylitis (AS), Chills, Cold, Common Cold, Cough, Cough caused by Common Cold, Coughing caused by Flu caused by Influenza, Dyskinesia of the Biliary Tract, Dyskinesia of the Urinary Tract, Febrile Convulsions, Febrile Illness Acute, Fever, Fibromyalgia, Flu caused by Influenza, Headache, Joint dislocations, Menstrual Distress (Dysmenorrhea), Mild pain, Muscle Inflammation, Muscle Injuries, Muscle Spasms, Musculoskeletal Pain, Myalgia, Nasal Congestion, Neuropathic Pain, Osteoarthritis (OA), Pain, Postoperative pain, Premenstrual cramps, Rheumatoid Arthritis, Rhinopharyngitis, Rhinorrhoea, Severe Pain, Sinusitis, Spasms, Spastic Pain of the Gastrointestinal Tract, Sprains, Symptoms Cold, Tension Headache, Toothache, Upper Respiratory Tract Infection, Whiplash Syndrome, Acute Torticollis, Articular inflammation, Cold or flu syndrome, Mild to moderate pain, Minor aches and pains, Minor pain, Moderate Pain, Moderate to severe pain

Associated Therapies: Airway secretion clearance therapy, Anti-spasmodics, Bronchodilation

Clinical Trials

Different Approaches for the Management of Post-dural Puncture Headache

Not Applicable

Completed

Conditions: Post-Dural Puncture Headache

Interventions: Procedure: sphenopalatine ganglion block
Drug: paracetamol

First Posted Date: 2022-02-23

Last Posted Date: 2022-02-23

Lead Sponsor: Bahaa Mohammed Refaie

Target Recruit Count: 120

Registration Number: NCT05253014

Locations: 🇪🇬
Sohag faculty of medicine, Sohag, Egypt

IV Acetaminophen After Cardiac Surgery - PILOT

Phase 3

Recruiting

Conditions: Delirium

Interventions: Drug: acetaminophen

First Posted Date: 2022-02-18

Last Posted Date: 2024-02-28

Lead Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre

Target Recruit Count: 900

Registration Number: NCT05246644

Locations: 🇨🇦
McGill University Health Centre, Montreal, Quebec, Canada
🇨🇦
Montreal Heart Institute, Montreal, Quebec, Canada

Effect of Local Anesthesia Versus Induced Hypotensive Anesthesia on Quality of External Dacryocystorhinostomy Operation

Not Applicable

Conditions: Patient With Nasolacrimal Duct Obstruction
External Dacryocystorhinostomy Operation

Interventions: Drug: Bupivacaine
Drug: Nitroglycerine
Drug: Propofol
Drug: Fentanyl
Drug: Atracurium Besylate
Procedure: Mechanical ventilation
Drug: Sevoflurane
Drug: Lactated Ringers
Other: Head-up tilt
Drug: Paracetamol

First Posted Date: 2022-02-15

Last Posted Date: 2022-02-15

Lead Sponsor: Mansoura University

Target Recruit Count: 64

Registration Number: NCT05241054

Locations: 🇪🇬
Mansoura University, Mansoura, DK, Egypt

Paracetamol Vs Caffeine Vs Codeine in the Management of Post Traumatic Pain in Emergencies

Phase 3

Completed

Conditions: Acute Pain Due to Trauma

Interventions: Drug: Paracetamol Codeine
Drug: Paracetamol caféine
Drug: Paracetamol

First Posted Date: 2022-02-08

Last Posted Date: 2023-06-28

Lead Sponsor: University of Monastir

Target Recruit Count: 1500

Registration Number: NCT05229965

Locations: 🇹🇳
Nouira Semir, Monastir, Tunisia

Preemptive Dexamethasone , Paracetamol on Postoperative Period Following Adeno-tonsillectomy in Pediatric .

Phase 2

Completed

Conditions: Analgesia

Interventions: Drug: paracetamol
Drug: normal Saline
Drug: Dexamethasone

First Posted Date: 2021-12-03

Last Posted Date: 2022-05-09

Lead Sponsor: Benha University

Target Recruit Count: 90

Registration Number: NCT05143762

Locations: 🇪🇬
Banha Faculity of Medicine, Banha, Elqalyoubea, Egypt

Analgesic Use for Pain Relief in Scorpion Sting

Not Applicable

Completed

Conditions: Scorpion Stings

Interventions: Drug: Lidocaine topical
Drug: Dexketoprofen Trometamol
Drug: Placebo
Drug: paracetamol

First Posted Date: 2021-11-18

Last Posted Date: 2024-02-08

Lead Sponsor: Adiyaman University Research Hospital

Target Recruit Count: 106

Registration Number: NCT05125796

Locations: 🇹🇷
Adiyaman University Research Hospital, Adıyaman, Central, Turkey

A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE. Master Protocol HTX-011-401.

Phase 4

Active, not recruiting

Conditions: Analgesia

Interventions: Drug: HTX-011
Drug: Bupivacaine Hydrochloride
Device: Luer lock applicator
Drug: Ibuprofen
Drug: Acetaminophen

First Posted Date: 2021-11-05

Last Posted Date: 2023-10-26

Lead Sponsor: Heron Therapeutics

Target Recruit Count: 90

Registration Number: NCT05109312

Locations: 🇺🇸
Endeavor Clinical Trials, LLC, San Antonio, Texas, United States
🇺🇸
First Surgical Hospital, Bellaire, Texas, United States
🇺🇸
Legent Orthopedic Hospital, Carrollton, Texas, United States

and more 4 locations

Paracetamol in Addition to WHO Step III Opioids in Chronic Cancer Pain Control

Phase 4

Recruiting

Conditions: Pain

Interventions: Drug: Placebo
Drug: Paracetamol

First Posted Date: 2021-10-22

Last Posted Date: 2024-08-13

Lead Sponsor: Insel Gruppe AG, University Hospital Bern

Target Recruit Count: 140

Registration Number: NCT05088876

Locations: 🇨🇭
Kantonsspital Baden, Baden, Switzerland
🇨🇭
St. Claraspital AG, Basel, Switzerland
🇨🇭
Inselspital, Bern University Hospital, Bern, Switzerland