Dexmedetomidine
- Generic Name
- Dexmedetomidine
- Brand Names
- Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16N2
- CAS Number
- 113775-47-6
- Unique Ingredient Identifier
- 67VB76HONO
- Background
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
- Indication
Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder.
- Associated Conditions
- Agitation, Alcohol Withdrawal Syndrome
- Associated Therapies
- -
Comparison of Two Sedation Regimens for Awake Fiberoptic Intubation
- First Posted Date
- 2023-02-21
- Last Posted Date
- 2024-11-28
- Lead Sponsor
- University of Illinois at Chicago
- Target Recruit Count
- 96
- Registration Number
- NCT05736198
- Locations
- 🇺🇸
University of Illinois, Chicago, Illinois, United States
Dexmedetomidine-esketamine Combined Nasal Administration and Perioperative Sleep Quality
- Conditions
- Interventions
- First Posted Date
- 2023-02-16
- Last Posted Date
- 2023-05-25
- Lead Sponsor
- Peking University First Hospital
- Target Recruit Count
- 180
- Registration Number
- NCT05732064
- Locations
- 🇨🇳
Peking University First Hospital, Beijin, Bejing, China
Dexmedetomidine Infusion and Surgical Pleth Index In Pediatrics
- Conditions
- Interventions
- First Posted Date
- 2023-02-14
- Last Posted Date
- 2024-02-22
- Lead Sponsor
- Fayoum University Hospital
- Target Recruit Count
- 90
- Registration Number
- NCT05727969
- Locations
- 🇪🇬
Fayoum University hospital, Madīnat al Fayyūm, Faiyum Governorate, Egypt
A Comparative Evaluation of Nebulized Dexmedetomidine and Nebulized Ketamine as a Premedication in Pediatric Surgeries
- Conditions
- Interventions
- First Posted Date
- 2023-02-09
- Last Posted Date
- 2023-02-09
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 60
- Registration Number
- NCT05719506
- Locations
- 🇪🇬
Tanta University Hospitals, Tanta, Egypt
🇪🇬Tanta University, Tanta, Egypt
Prevention of Shivering After Spinal Anesthesia
- First Posted Date
- 2023-02-08
- Last Posted Date
- 2023-02-08
- Lead Sponsor
- Pakistan Air Force (PAF) Hospital Islamabad
- Target Recruit Count
- 116
- Registration Number
- NCT05718011
- Locations
- 🇵🇰
PAF Hospital Islamabad, Islamabad, Federal, Pakistan
Mini-dose Esketamine-dexmedetomidine Supplemented Analgesia and Long-term Outcomes
- Conditions
- Interventions
- First Posted Date
- 2023-02-08
- Last Posted Date
- 2023-02-09
- Lead Sponsor
- Peking University First Hospital
- Target Recruit Count
- 199
- Registration Number
- NCT05718544
- Locations
- 🇨🇳
Peking University First Hospital, Beijing, Beijing, China
Dexmedetomidine in Postoperative Analgesia
- First Posted Date
- 2023-01-30
- Last Posted Date
- 2024-11-14
- Lead Sponsor
- New Valley University
- Target Recruit Count
- 100
- Registration Number
- NCT05705128
- Locations
- 🇪🇬
Assiut University Hospital, Assiut, Egypt
The Effect of Esmolol Versus Dexmedetomidine on Postoperative Pain Control in Endoscopic Sinus Surgery: A Randomized Trial
- Conditions
- Interventions
- First Posted Date
- 2023-01-27
- Last Posted Date
- 2023-11-24
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 70
- Registration Number
- NCT05703048
- Locations
- 🇪🇬
Faculty of Medicine, Tantan University Hospital, Tanta, Egypt
Dexmedetomidine-Ropivacine Versus Sufentanil-Ropivacaine for Epidural Labor Analgesia
- First Posted Date
- 2023-01-26
- Last Posted Date
- 2024-01-03
- Lead Sponsor
- Peking University First Hospital
- Target Recruit Count
- 200
- Registration Number
- NCT05698407
- Locations
- 🇨🇳
Peking University First Hospital, Beijin, Bejing, China
TAP Using Dexmedetomidine and Ropivacaine for Cesarean Section Analgesia
- Conditions
- Interventions
- First Posted Date
- 2023-01-26
- Last Posted Date
- 2023-10-11
- Lead Sponsor
- Xijing Hospital
- Target Recruit Count
- 90
- Registration Number
- NCT05700045
- Locations
- 🇨🇳
Huang Nie, Xi'an, China
🇨🇳The Fourth military medical university, Xijing Hospital, Xi'an, Shannxi, China
Drug Development Updates
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