Dexmedetomidine

Generic Name
Dexmedetomidine
Brand Names
Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
Drug Type
Small Molecule
Chemical Formula
C13H16N2
CAS Number
113775-47-6
Unique Ingredient Identifier
67VB76HONO
Background

An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.

Indication

Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film...

Associated Conditions
Agitation, Alcohol Withdrawal Syndrome
Associated Therapies
-

Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Knee Arthroplasty

First Posted Date
2024-06-24
Last Posted Date
2024-06-24
Lead Sponsor
Poznan University of Medical Sciences
Target Recruit Count
90
Registration Number
NCT06470100
Locations
🇵🇱

Poznan University of Medical Sciences, Poznan, Poznań, Poland

Dexmedetomidine-Esketamine Combination for Sedation and Analgesia in ICU Patients

First Posted Date
2024-06-21
Last Posted Date
2024-10-08
Lead Sponsor
Peking University First Hospital
Target Recruit Count
1508
Registration Number
NCT06468436
Locations
🇨🇳

Peking University First Hospital, Beijing, Beijing, China

🇨🇳

Tianjin Medical University General Hospital, Tianjin, Tianjin, China

🇨🇳

Peking University International Hospital, Beijing, Beijing, China

Propofol vs. Nasal Dexmedetomidine in Pediatric Agitation and Delirium

First Posted Date
2024-06-20
Last Posted Date
2024-06-20
Lead Sponsor
Baskent University Ankara Hospital
Target Recruit Count
162
Registration Number
NCT06466915
Locations
🇹🇷

Ahmed Uslu, Ankara, Çankaya, Turkey

Dexmedetomidine Versus Midazolam-Fentanyl for Analgesia and Sedation

Not Applicable
Recruiting
Conditions
Interventions
First Posted Date
2024-06-18
Last Posted Date
2024-06-18
Lead Sponsor
Egymedicalpedia
Target Recruit Count
60
Registration Number
NCT06464263
Locations
🇪🇬

Al-Azhar University hospitals, Cairo, Egypt

Dexmedetomidine as an Adjuvant to Bupivacaine in Bilateral PECs for Pain Control After Cardiac Surgeries

First Posted Date
2024-06-12
Last Posted Date
2024-06-14
Lead Sponsor
Kasr El Aini Hospital
Target Recruit Count
60
Registration Number
NCT06453681
Locations
🇪🇬

Kasralainy school of medicine, Cairo, Egypt

🇪🇬

Kasralaini Faculty of Medicine, Cairo, Egypt

Articaine Plus Dexmedetomidine in Supraclavicular Block

Not Applicable
Recruiting
Conditions
Interventions
First Posted Date
2024-05-21
Last Posted Date
2024-05-23
Lead Sponsor
Benha University
Target Recruit Count
66
Registration Number
NCT06423859
Locations
🇪🇬

Samar Rafik Mohamed Amin, Banhā, Qalubia, Egypt

Intrathecal Dexmedetomidine vs Epinephrine

First Posted Date
2024-05-17
Last Posted Date
2024-10-11
Lead Sponsor
Icahn School of Medicine at Mount Sinai
Target Recruit Count
90
Registration Number
NCT06418308
Locations
🇺🇸

Mount Sinai Hospital, New York, New York, United States

Propofol Versus Dexmedetomidine for Sedation of Cancer Patients Undergoing ERCP

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2024-05-10
Last Posted Date
2024-05-14
Lead Sponsor
National Cancer Institute, Egypt
Target Recruit Count
202
Registration Number
NCT06409104
Locations
🇪🇬

Ahmed Mohamed Soliman, Giza, Egypt

Perioperative Multimodal Analgesia Protocol for Supratentorial Craniotomy

First Posted Date
2024-05-09
Last Posted Date
2024-05-14
Lead Sponsor
Beijing Tiantan Hospital
Target Recruit Count
2000
Registration Number
NCT06406829
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