Dexmedetomidine

Generic Name
Dexmedetomidine
Brand Names
Dexdor, Igalmi, Precedex, Dexmedetomidine Accord
Drug Type
Small Molecule
Chemical Formula
C13H16N2
CAS Number
113775-47-6
Unique Ingredient Identifier
67VB76HONO
Background

An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.

Indication

Administered intravenously, dexmedetomidine is indicated for the sedation of initially intubated and mechanically ventilated patients during treatment in intensive care settings, and for the sedation of non-intubated patients prior to and/or during surgery and other procedures. It is also available as a buccally- or sublingually-administered dissolvable film...

Associated Conditions
Agitation, Alcohol Withdrawal Syndrome
Associated Therapies
-
Clinical Trials
Related News

Stellate Ganglion Block Combined With Dexmedetomidine or Subanesthetic Ketamine Infusion for Treatment of Neurostorm.

First Posted Date
2024-04-09
Last Posted Date
2024-04-10
Lead Sponsor
Zagazig University
Target Recruit Count
205
Registration Number
NCT06354673
Locations
🇪🇬

Zagazig university, Zagazig, Egypt

The Efficacy of Dexmedetomidine Versus Labetalol In Providing Controlled Hypotension In Dacryocystorhinostomy SurgeryA Comparative Randomized Prospective Study

Not Applicable
Recruiting
Conditions
Nasolacrimal Duct Obstruction
Interventions
Drug: Dexmedetomidine
Drug: Labetalol
First Posted Date
2024-04-04
Last Posted Date
2024-04-04
Lead Sponsor
Sohag University
Target Recruit Count
50
Registration Number
NCT06346561
Locations
🇪🇬

Sohag University hospitals, Sohag, Egypt

Dexmedetomidine and Ketamine as an Adjuvant in External Oblique Intercostal Plane Block for Post Thoracotomy Pain

First Posted Date
2024-03-26
Last Posted Date
2024-03-27
Lead Sponsor
Tanta University
Target Recruit Count
40
Registration Number
NCT06331182
Locations
🇪🇬

Tanta University, Tanta, ElGharbia, Egypt

Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery

First Posted Date
2024-03-25
Last Posted Date
2024-05-14
Lead Sponsor
Boston Children's Hospital
Target Recruit Count
58
Registration Number
NCT06326983
Locations
🇺🇸

Boston Children's Hospital, Waltham, Massachusetts, United States

Intrathecal Dexmedetomidine vs Midazolame

First Posted Date
2024-03-18
Last Posted Date
2024-03-18
Lead Sponsor
National Cancer Institute, Egypt
Target Recruit Count
75
Registration Number
NCT06315634
Locations
🇪🇬

National cancer institute, Cairo, Egypt

Propofol Versus Dexmedetomidine Effect on Prevention Emergence Agitation

Phase 4
Recruiting
Conditions
Emergence Agitation
Interventions
Drug: Propofol
Drug: Dexmedetomidine
First Posted Date
2024-03-15
Last Posted Date
2024-11-06
Lead Sponsor
Ain Shams University
Target Recruit Count
30
Registration Number
NCT06312618
Locations
🇪🇬

Ain Shams University, Cairo, Egypt

Dexamethasone Versus Dexmedetomidine as Adjuncts to Serratus Anterior Plane Block

Phase 4
Not yet recruiting
Conditions
Breast Cancer
Interventions
Drug: Dexamethasone
Drug: Dexmedetomidine
First Posted Date
2024-03-08
Last Posted Date
2024-03-12
Lead Sponsor
Al-Azhar University
Target Recruit Count
126
Registration Number
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Study Evaluating Dexmedetomidine in the Acute Treatment of Electrical Storm

First Posted Date
2024-02-28
Last Posted Date
2024-06-05
Lead Sponsor
Ottawa Heart Institute Research Corporation
Target Recruit Count
192
Registration Number
NCT06281977
Locations
🇨🇦

University of Ottawa Heart Institute, Ottawa, Ontario, Canada

Dexmedetomidine Premedication for Post-anaesthesia Sleep Disturbance

Phase 3
Not yet recruiting
Conditions
Postoperative Sleep Disturbance
Interventions
Drug: Dexmedetomidine
Drug: Normal Saline
First Posted Date
2024-02-28
Last Posted Date
2024-04-16
Lead Sponsor
The First Affiliated Hospital of Xiamen University
Target Recruit Count
110
Registration Number
NCT06281561

Dexmedetomidine vs. Remifentanil Conscious Sedation for Stapedotomy/Stapedectomy

Not Applicable
Recruiting
Conditions
Otosclerosis
Interventions
Drug: Dexmedetomidine
Drug: Remifentanil
First Posted Date
2024-02-28
Last Posted Date
2024-08-28
Lead Sponsor
Iuliu Hatieganu University of Medicine and Pharmacy
Target Recruit Count
100
Registration Number
NCT06283836
Locations
🇷🇴

Cluj County Clinical Emergency Hospital, Cluj Napoca, Cluj, Romania

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