Colchicine
- Generic Name
- Colchicine
- Brand Names
- Colcrys, Gloperba, Lodoco, Mitigare
- Drug Type
- Small Molecule
- Chemical Formula
- C22H25NO6
- CAS Number
- 64-86-8
- Unique Ingredient Identifier
- SML2Y3J35T
- Background
Colchicine is an alkaloid drug derived from a plant belonging to the Lily family, known as Colchicum autumnale, or "autumn crocus." Its use was first approved by the FDA in 1961. Colchicine is used in the treatment of gout flares and Familial Mediterranean fever, and prevention of major cardiovascular events. It has also been investigated in other inflammato...
- Indication
Colchicine is indicated for the prophylaxis and treatment of gout flares. It is also indicated in Familial Mediterranean fever (FMF) in children and adults of four years of age and older. It is also indicated to reduce the risk of myocardial infarction (MI), stroke, coronary revascularization, and cardiovascular death in adult patients with established ather...
- Associated Conditions
- Behcet's Syndrome, Cardiovascular Mortality, Coronary Revascularization, Familial Mediterranean Fever (FMF ), Gout Flares, Myocardial Infarction, Pericarditis, Postpericardiotomy Syndrome, Stroke
- Associated Therapies
- -
Colchicine to Prevent Post-Pericardiotomy Syndrome and Atrial Fibrillation
- Conditions
- Interventions
- First Posted Date
- 2014-06-27
- Last Posted Date
- 2017-06-21
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 2
- Registration Number
- NCT02177266
- Locations
- 🇺🇸
Mayo Clinic, Rochester, Minnesota, United States
Colchicine for Symptom and Inflammation in Knee Osteoarthritis
- First Posted Date
- 2014-06-27
- Last Posted Date
- 2016-04-15
- Lead Sponsor
- Singapore General Hospital
- Target Recruit Count
- 109
- Registration Number
- NCT02176460
- Locations
- 🇸🇬
Singapore General Hospital, Singapore, Singapore
Colchicine in Vascular Inflammation Assessed With PET Imaging
- Conditions
- Interventions
- First Posted Date
- 2014-06-12
- Last Posted Date
- 2020-02-21
- Lead Sponsor
- Montreal Heart Institute
- Target Recruit Count
- 106
- Registration Number
- NCT02162303
- Locations
- 🇨🇦
Montreal Heart Institute, Montreal, Quebec, Canada
Anti-platelet Effects of Colchicine in Healthy Volunteers
- First Posted Date
- 2014-05-16
- Last Posted Date
- 2016-02-23
- Lead Sponsor
- NYU Langone Health
- Target Recruit Count
- 10
- Registration Number
- NCT02140372
- Locations
- 🇺🇸
New York University School of Medicine, New York, New York, United States
Efficacy and Safety of Extended Release and Immediate Release Febuxostat in Participants With Gout
- Conditions
- Interventions
- First Posted Date
- 2014-05-15
- Last Posted Date
- 2016-11-03
- Lead Sponsor
- Takeda
- Target Recruit Count
- 1790
- Registration Number
- NCT02139046
Efficacy and Safety of Extended Release and Immediate Release Febuxostat in Participants With Gout and Moderate Renal Impairment
- Conditions
- Interventions
- First Posted Date
- 2014-05-01
- Last Posted Date
- 2016-11-03
- Lead Sponsor
- Takeda
- Target Recruit Count
- 189
- Registration Number
- NCT02128490
- Locations
- 🇺🇸
Benny Green MD PA Family Practice, Little Rock, Arkansas, United States
🇺🇸Long Beach Center for Clinical Research, Long Beach, California, United States
🇺🇸Central Kentucy Reseach Associates, Lexington, Kentucky, United States
Colchicine in Coronary Artery Bypass Graft (CABG)
- Conditions
- Interventions
- First Posted Date
- 2014-04-24
- Last Posted Date
- 2014-11-11
- Lead Sponsor
- G.Gennimatas General Hospital
- Target Recruit Count
- 60
- Registration Number
- NCT02122484
- Locations
- 🇬🇷
Athens General Hospital "G. Gennimatas", Athens, Attika, Greece
COlchicine Improve EnDothElial Function in Non ST Elevation Myocardial Infarction Patients
- First Posted Date
- 2014-03-24
- Last Posted Date
- 2016-07-07
- Lead Sponsor
- Tel-Aviv Sourasky Medical Center
- Registration Number
- NCT02095522
- Locations
- 🇮🇱
Tel Aviv Medical Center, Tel Aviv, Israel
🇮🇱Sourasky medical center (Ichilov), Tel-Aviv, Israel
Apolipoprotein CIII Reduction Via Colchicine
- First Posted Date
- 2014-03-11
- Last Posted Date
- 2014-05-30
- Lead Sponsor
- Scripps Translational Science Institute
- Target Recruit Count
- 5
- Registration Number
- NCT02083510
- Locations
- 🇺🇸
Scripps Translational Science Institute, La Jolla, California, United States
Immune Molecular and Inflammatory Cytokines Dysfunction Analysis in Gout Patients With Different Urate Levels
- First Posted Date
- 2014-02-12
- Last Posted Date
- 2014-05-08
- Lead Sponsor
- Tongji Hospital
- Target Recruit Count
- 96
- Registration Number
- NCT02060552
- Locations
- 🇨🇳
Yikai YU, Wuhan, Hubei, China
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.