Metoclopramide

Generic Name
Metoclopramide
Brand Names
Gimoti, Reglan
Drug Type
Small Molecule
Chemical Formula
C14H22ClN3O2
CAS Number
364-62-5
Unique Ingredient Identifier
L4YEB44I46
Background

Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to gastroesophageal reflux disease (GER...

Indication

Metoclopramide in the oral tablet form is used for symptomatic treatment of both acute and recurrent diabetic gastroparesis, in addition to the treatment of gastroesophageal reflux disease (GERD) in patients who have failed to respond to traditional therapy. A nasal spray formulation is also indicated to treat adults with acute, recurrent diabetic gastropare...

Associated Conditions
Chemotherapy-Induced Nausea and Vomiting, Diabetic Gastroparesis, Dyspepsia, Flatulence, Gastroesophageal Reflux, Gastroparesis, Hiccups, Hyperacidity, Migraine, Nausea and vomiting, Post Operative Nausea and Vomiting (PONV), Radiation-Induced Nausea and Vomiting, Acute, recurrent Diabetic Gastroparesis, Gastric bezoar
Associated Therapies
Facilitation of small bowel intubation therapy, Gastric emptying for radiologic procedures
finance.yahoo.com
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Gastroparesis Drugs Market size to increase by USD 1.42 Billion between 2023 to 2028

The global gastroparesis drugs market is projected to grow by USD 1.42 billion from 2024 to 2028, with a CAGR of 3.69%. Key segments include drug class, disease type, and geography. Prokinetic drugs like metoclopramide and domperidone are significant for managing symptoms. New drugs under development aim to improve treatment outcomes.
prnewswire.com
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Gastroparesis Drugs Market to Grow by USD 1.42 Billion from 2024-2028, Driven by Rising ...

Global gastroparesis drugs market to grow by USD 1.42 billion from 2024-2028, driven by rising diabetes prevalence and emerging market opportunities, despite stringent regulatory challenges. Key players include Abbott Laboratories, AbbVie Inc., and others.
drugstorenews.com
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Avenacy intros generic Reglan

Avenacy, a specialty pharmaceutical company, offers Metoclopramide Injection, a generic of ANI's Reglan, indicated for diabetic gastroparesis, nausea prevention, and more. Available in 10 mg/2 ml vials, it features differentiated packaging for patient safety. Supported by a global network of cGMP-compliant partners, Avenacy aims to expand its product portfolio.
morningstar.com
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Evoke Pharma Reaffirms Its Commitment to Patients with Gastroparesis Amid Industry Developments

Evoke Pharma reaffirms commitment to improving diabetic gastroparesis treatment with Gimoti nasal spray after FDA's rejection of Vanda Pharmaceuticals' Tradipitant.
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