Metoclopramide

Generic Name
Metoclopramide
Brand Names
Gimoti, Reglan
Drug Type
Small Molecule
Chemical Formula
C14H22ClN3O2
CAS Number
364-62-5
Unique Ingredient Identifier
L4YEB44I46
Background

Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to gastroesophageal reflux disease (GER...

Indication

Metoclopramide in the oral tablet form is used for symptomatic treatment of both acute and recurrent diabetic gastroparesis, in addition to the treatment of gastroesophageal reflux disease (GERD) in patients who have failed to respond to traditional therapy. A nasal spray formulation is also indicated to treat adults with acute, recurrent diabetic gastropare...

Associated Conditions
Chemotherapy-Induced Nausea and Vomiting, Diabetic Gastroparesis, Dyspepsia, Flatulence, Gastroesophageal Reflux, Gastroparesis, Hiccups, Hyperacidity, Migraine, Nausea and vomiting, Post Operative Nausea and Vomiting (PONV), Radiation-Induced Nausea and Vomiting, Acute, recurrent Diabetic Gastroparesis, Gastric bezoar
Associated Therapies
Facilitation of small bowel intubation therapy, Gastric emptying for radiologic procedures

Efficacy of Haloperidol vs. Metoclopramide for Treatment of Acute Headaches and Migraines in the Emergency Department

First Posted Date
2016-11-23
Last Posted Date
2018-10-23
Lead Sponsor
OhioHealth
Target Recruit Count
66
Registration Number
NCT02972502
Locations
🇺🇸

OhioHealth Doctors Hospital, Columbus, Ohio, United States

The Effect of Dopamine on Pulmonary Diffusion and Capillary Blood Volume During Exercise

First Posted Date
2016-11-17
Last Posted Date
2024-12-04
Lead Sponsor
University of Alberta
Target Recruit Count
35
Registration Number
NCT02965963
Locations
🇨🇦

Clinical Physiology Research Laboratory, Edmonton, Alberta, Canada

Acupuncture Point P6 Stimulation for Reduction of Nausea and Vomiting During Cesarean

First Posted Date
2016-11-09
Last Posted Date
2017-09-25
Lead Sponsor
Rutgers, The State University of New Jersey
Target Recruit Count
180
Registration Number
NCT02959840
Locations
🇺🇸

Robert Wood Johnson University Hospital, New Brunswick, New Jersey, United States

Effects of Morphine on Loading-dose Ticagrelor in Patients With ST-segment Elevation Myocardial Infarction

First Posted Date
2016-09-23
Last Posted Date
2020-03-31
Lead Sponsor
General Hospital of Chinese Armed Police Forces
Target Recruit Count
128
Registration Number
NCT02913469
Locations
🇨🇳

Cardiology Department, Chinese Armed Police Force Genral Hospital, Beijing China, Beijing, China

Methoclopramide for Gastroesophageal Reflux in Premature Infants

Phase 4
Completed
Conditions
Interventions
First Posted Date
2016-09-20
Last Posted Date
2020-09-02
Lead Sponsor
Nathalie Charpak
Target Recruit Count
490
Registration Number
NCT02907632
Locations
🇨🇴

Nathalie Charpak, Bogotá, Cundinamarca, Colombia

Corticosteroids for Acute Migraine in the Emergency Department

First Posted Date
2016-07-28
Last Posted Date
2019-01-08
Lead Sponsor
Montefiore Medical Center
Target Recruit Count
220
Registration Number
NCT02847494
Locations
🇺🇸

Montefiore Medical Center-Moses, Bronx, New York, United States

🇺🇸

Montefiore Medical Center--Einstein, Bronx, New York, United States

Efficacy, Safety, and Pharmacokinetics (PK) Study of Ulimorelin in Patients With Enteral Feeding Intolerance (EFI): The PROMOTE Trial

First Posted Date
2016-05-27
Last Posted Date
2018-03-07
Lead Sponsor
Lyric Pharmaceuticals
Target Recruit Count
120
Registration Number
NCT02784392

Impact of Morphine Treatment on Platelet Inhibition in Acute Myocardial Infarction

First Posted Date
2015-12-11
Last Posted Date
2019-08-08
Lead Sponsor
University of Luebeck
Target Recruit Count
138
Registration Number
NCT02627950
Locations
🇩🇪

University of Luebeck, Luebeck, Germany

Antiemetic Efficacy of Ondansetron Versus Metoclopramide

First Posted Date
2015-12-02
Last Posted Date
2015-12-02
Lead Sponsor
Hospital General Naval de Alta Especialidad - Escuela Medico Naval
Target Recruit Count
250
Registration Number
NCT02619201
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