Carrick Therapeutics' CDK7 inhibitor samuraciclib demonstrated significantly extended progression-free survival in HR+ advanced breast cancer patients without TP53 mutations or liver metastases in two independent Phase 2 trials.
Sanofi discontinues the development of amcenestrant, an oral selective estrogen receptor degrader (SERD), after it failed in the AMEERA-5 phase 3 trial.
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