Papaverine
- Generic Name
- Papaverine
- Drug Type
- Small Molecule
- Chemical Formula
- C20H21NO4
- CAS Number
- 58-74-2
- Unique Ingredient Identifier
- DAA13NKG2Q
- Background
An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
- Indication
For the treatment of impotence and vasospasms.
- Associated Conditions
- Vascular spasm, Visceral spasms
Optimal Analgesia in Acute Gastroenteritis
- First Posted Date
- 2016-03-17
- Last Posted Date
- 2016-03-17
- Lead Sponsor
- Hadassah Medical Organization
- Target Recruit Count
- 15
- Registration Number
- NCT02711241
- Locations
- 🇮🇱
Hadssah Medical Organisation, Jerusalem, Israel
Phosphodiesterase (PDE) Inhibitors Effect on Cognitive Deficits Associated to Schizophrenia
- Conditions
- SchizophreniaCognitive Deficits
- Interventions
- First Posted Date
- 2013-03-19
- Last Posted Date
- 2015-05-28
- Lead Sponsor
- University of Copenhagen
- Target Recruit Count
- 5
- Registration Number
- NCT01813955
- Locations
- 🇩🇰
Glostrup psychiatric center, Glostrup, Denmark
Nerve-Sparing Radical Prostatectomy With or Without Nerve Grafting Followed by Standard Therapy for Erectile Dysfunction in Treating Patients With Localized Prostate Cancer
- Conditions
- Prostate Cancer
- Interventions
- Procedure: conventional surgery
- First Posted Date
- 2004-04-08
- Last Posted Date
- 2012-07-30
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 111
- Registration Number
- NCT00080808
- Locations
- 🇺🇸
M.D. Anderson Cancer Center at University of Texas, Houston, Texas, United States
Drug Development Updates
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