Solifenacin

Generic Name
Solifenacin
Brand Names
Vesicare
Drug Type
Small Molecule
Chemical Formula
C23H26N2O2
CAS Number
242478-37-1
Unique Ingredient Identifier
A8910SQJ1U
Background

Solifenacin is a competitive muscarinic receptor antagonist indicated to treat an overactive bladder with urinary incontinence, urgency, and frequency. It has a long duration of action as it is usually taken once daily.

Solifenacin was granted FDA approval on 19 November 2004.

Indication

Solifenacin tablets are indicated to treat an overactive bladder with urinary incontinence, urgency, and frequency.

Associated Conditions
Benign Prostatic Hyperplasia (BPH), Overactive Bladder Syndrome (OABS)
Associated Therapies
-

Efficacy of Solifenacin, Mirabegron and Combination Therapy in Children With Daytime Urinary Incontinence (BeDry)

First Posted Date
2024-08-13
Last Posted Date
2024-08-13
Lead Sponsor
University of Aarhus
Target Recruit Count
236
Registration Number
NCT06551246
Locations
🇩🇰

Department of Pediatric and Adolescent Medicine, Aarhus University Hospital, Aarhus, Aarhus N, Denmark

🇩🇰

Department of Pediatric and Adolescent Medicine, Aalborg University Hospital, Aalborg, Denmark

🇩🇰

Department of Pediatric and Adolescent medicine, Esbjerg Hospital, Esbjerg, Denmark

and more 2 locations

Efficacy and Safety of VDS+SU in the Treatment of OAB-dry in Children

First Posted Date
2024-07-08
Last Posted Date
2024-10-23
Lead Sponsor
Xing Liu
Target Recruit Count
180
Registration Number
NCT06489951
Locations
🇨🇳

Children's Hospital of Chongqing Medical University, Chongqing, Chongqing, China

Strategy for Withdrawal of Pharmacological Treatment for Urinary Incontinence in Children (StayDry)

First Posted Date
2024-06-20
Last Posted Date
2024-06-26
Lead Sponsor
University of Aarhus
Target Recruit Count
216
Registration Number
NCT06465576
Locations
🇩🇰

Department of Pediatric and Adolescent medicine, Esbjerg Hospital, Esbjerg, Denmark

🇩🇰

Department of Pediatric and Adolescent Medicine, Aarhus University Hospital, Aarhus, Aarhus N, Denmark

🇩🇰

Department of Pediatric and Adolescent Medicine, Aalborg University Hospital, Aalborg, Denmark

and more 2 locations

Efficacy and Safety of Vitamin D in the Treatment of OAB-wet in Children

First Posted Date
2024-01-11
Last Posted Date
2024-01-11
Lead Sponsor
Xing Liu
Target Recruit Count
150
Registration Number
NCT06201013
Locations
🇨🇳

Children's Hospital of Chongqing Medical University, Chongqing, Chongqing, China

Pharmacologic Effect for Female Overactive Bladder Syndrome: Mirabegron Versus Solifenacin

Phase 3
Recruiting
Conditions
Interventions
First Posted Date
2019-07-17
Last Posted Date
2023-09-15
Lead Sponsor
Far Eastern Memorial Hospital
Target Recruit Count
120
Registration Number
NCT04023253
Locations
🇨🇳

Department of Obstetrics and Gynecology, Far-Eastern Memorial Hospital, Banqiao, New Taipei, Taiwan

Electroacupuncture and Solifenacin for Urgency-predominant Mixed Urinary Incontinence

First Posted Date
2018-12-26
Last Posted Date
2022-02-04
Lead Sponsor
Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Target Recruit Count
282
Registration Number
NCT03787654
Locations
🇨🇳

Guang An Men Hospital, Beijing, China

Treatment Persistence Among Patients With Overactive Bladder: A Retrospective Secondary Data Analysis in Asia Oceania

First Posted Date
2018-07-27
Last Posted Date
2024-10-16
Lead Sponsor
Astellas Pharma Singapore Pte. Ltd.
Target Recruit Count
5589
Registration Number
NCT03602508
Locations
🇦🇺

Site AU10000, Sydney, Australia

🇰🇷

Site KR82001, Seoul, Korea, Republic of

Peripheral Transcutaneous Neuromodulation of the Post-tibial Nerve for Solifenacin 10 mg. Hyperactive Bladder Syndrome

First Posted Date
2018-03-16
Last Posted Date
2018-08-02
Lead Sponsor
Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
Target Recruit Count
110
Registration Number
NCT03468465
Locations
🇪🇸

Hospital Clínico Universtario Virgen de la Arrixaca, El Palmar, Murcia, Spain

Behavioral or Solifenacin Therapy for Urinary Symptoms in Parkinson Disease

First Posted Date
2017-05-11
Last Posted Date
2023-10-25
Lead Sponsor
VA Office of Research and Development
Target Recruit Count
77
Registration Number
NCT03149809
Locations
🇺🇸

Atlanta VA Medical and Rehab Center, Decatur, GA, Decatur, Georgia, United States

🇺🇸

Birmingham VA Medical Center, Birmingham, AL, Birmingham, Alabama, United States

🇺🇸

Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, Philadelphia, Pennsylvania, United States

and more 1 locations
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