Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated in tumour cell proliferation and tumour angiogenesis. First approved by the FDA and European Commission in 2007 for the treatment of hepatocellular carcinoma, sorafenib is also indicated to ...
Sorafenib is indicated for the treatment of unresectable hepatocellular carcinoma and advanced renal cell carcinoma.
In the US, it is also indicated for the treatment of patients with locally recurrent or metastatic, progressive, differentiated thyroid carcinoma that is refractory to radioactive iodine treatment.
TaoBai, Nanning, Guangxi, China
TaoBai, Nanning, Guangxi, China
The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China
Cancer Center Sun Yat-sen University, Guangzhou, Guangdong, China
Beijing Ditan Hospital, Capital Medical University, Beijing, Beijing, China
Academic Medical Center, Amsterdam, Netherlands
Local Institution - 0295, Newark, New Jersey, United States
Local Institution - 0061, Salvador, Bahia, Brazil
Local Institution - 0038, Liverpool, New South Wales, Australia
Eastern Hepatobiliary Surgery Hospital, Shanghai, China
Humanity & Health Research Centre, Hong Kong, Hong Kong SAR, Hong Kong
OHSU Knight Cancer Institute, Portland, Oregon, United States
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