Butenafine
- Generic Name
- Butenafine
- Brand Names
- Lotrimin Ultra
- Drug Type
- Small Molecule
- Chemical Formula
- C23H27N
- CAS Number
- 101828-21-1
- Unique Ingredient Identifier
- 91Y494NL0X
Overview
Butenafine hydrochloride is a synthetic benzylamine antifungal agent. Butenafine's mechanism of action is believed to involve the synthesis inhibition of sterols. In particular, butenafine acts to inhibit the activity of the squalene epoxidase enzyme that is essential in the formation of sterols necessary for fungal cell membranes.
Background
Butenafine hydrochloride is a synthetic benzylamine antifungal agent. Butenafine's mechanism of action is believed to involve the synthesis inhibition of sterols. In particular, butenafine acts to inhibit the activity of the squalene epoxidase enzyme that is essential in the formation of sterols necessary for fungal cell membranes.
Indication
For the topical treatment of the following dermatologic infections: tinea (pityriasis) versicolor due to M. furfur, interdigital tinea pedis (athlete’s foot), tinea corporis (ringworm) and tinea cruris (jock itch) due to E. floccosum, T. mentagrophytes, T. rubrum, and T. tonsurans.
Associated Conditions
- Pityriasis versicolor
- Tinea Corporis
- Tinea Cruris
- Tinea Pedis
Clinical Trials
FDA Approved Products
Singapore Approved Products
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