Manufacturers: Xcel pharmaceuticals, Valeant pharmaceuticals international +8 more
Primidone is an antiepileptic used to treat grand mal, psychomotor, and focal epileptic seizures.
Primidone is an antiepileptic used to treat grand mal, psychomotor, and focal epileptic seizures.
Primidone and its metabolites, phenobarbital and phenylethylmalonamide (PEMA), are active anticonvulsants. Primidone does not directly interact with GABA-A receptors or chloride channels but phenobarbital does. Primidone alters transmembrane sodium and calcium channel transport, reducing the frequency of nerve firing, which may be responsible for the primidone’s effect on convulsions and essential tremor.
Primidone is commonly indicated for the management of grand mal, psychomotor, and focal epileptic seizures. In addition, it has also been studied and utilized as an effective management of essential tremor.
4 associated conditions
