Metronidazole

Generic Name
Metronidazole
Brand Names
Flagyl, Flagystatin, Likmez, Metrocream, Metrogel, Metrolotion, Nidagel, Noritate, Nuvessa, Pylera, Rosadan, Vandazole
Drug Type
Small Molecule
Chemical Formula
C6H9N3O3
CAS Number
443-48-1
Unique Ingredient Identifier
140QMO216E
Background

Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis, and amebiasis which are parasitic infections. Metronidazole has been used as an antibiotic for several decades, with added antiparasitic properties that set it ...

Indication

Metronidazole is indicated for the treatment of confirmed trichomoniasis caused by Trichomonas vaginalis (except for in the first trimester of pregnancy) and the patient's sexual partners, bacterial vaginosis, certain types of amebiasis, and various anaerobic infections. The above anaerobic infections may occur on the skin and skin structures, the abdomen, t...

Associated Conditions
Abscess Brain, Abscess, Intra-Abdominal, Anaerobic Bacterial Infection, Bacterial Endocarditis, Bacterial Peritonitis, Bacterial Septicemia, Bacterial Vaginosis (BV), Balantidiasis, Bone and Joint Infections, Central Nervous System Bacterial Infections, Empyema, Endometritis, Endomyometritis, Facial Rosacea, Giardiasis, Gynecological Infection, Helicobacter Pylori Infection, Inflammatory Papule, Inflammatory pustules, Liver Abscess, Amebic, Lower respiratory tract infection bacterial, Lung Abscess, Meningitis, Mixed Vaginal Infections, Mixed Vaginal Infections caused by Trichomonas Vaginalis, candida albicans, Periodontitis, Pneumonia, Postoperative Infections, Pouchitis, Skin and skin structure infections, Tetanus, Trichomonas Vaginitis, Tubo-ovarian abscess, Vaginal Candidiasis, Vaginitis Trichomonal, Vulvovaginitis, Acute Intestinal amebiasis, Asymptomatic Trichomoniasis, Entamoeba histolytica, Hepatic abscess, Intra-abdominal bacterial infections, Post-surgical vaginal cuff infection, Refractory Sinusitis, Symptomatic Trichomoniasis
Associated Therapies
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A "Screen and Treat" Helicobacter Pylori Eradication Trial in Adolescents in Three Regions of Chile

First Posted Date
2023-07-03
Last Posted Date
2024-12-20
Lead Sponsor
Miguel O'Ryan Gallardo
Target Recruit Count
500
Registration Number
NCT05926804
Locations
🇨🇱

Universidad de Chile, Santiago, Chile

🇨🇱

Universidad de Aysén, Coyhaique, Chile

🇨🇱

Universidad de la Frontera, Temuco, Chile

Doxycycline for Helicobacter Pylori Rescue Treatment

First Posted Date
2023-05-25
Last Posted Date
2023-09-25
Lead Sponsor
Shanghai Jiao Tong University School of Medicine
Target Recruit Count
368
Registration Number
NCT05874570
Locations
🇨🇳

Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, Shanghai, China

Rescue Therapy for Helicobacter Pylori Infection

First Posted Date
2023-05-25
Last Posted Date
2024-10-22
Lead Sponsor
Shanghai Jiao Tong University School of Medicine
Target Recruit Count
357
Registration Number
NCT05874544
Locations
🇨🇳

Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, Shanghai, China

🇨🇳

Shanghai Songjiang District Central Hospital, Shanghai, Shanghai, China

🇨🇳

The Second Affiliated Hospital of Zhejiang University school of Medicine, Hangzhou, Zhejiang, China

Standard Versus Prolonged Antibiotic Prophylaxis After Pancreatoduodenectomy (SPARROW)

Phase 4
Recruiting
Conditions
Interventions
First Posted Date
2023-03-24
Last Posted Date
2024-10-21
Lead Sponsor
Leiden University Medical Center
Target Recruit Count
344
Registration Number
NCT05784311
Locations
🇳🇱

Leiden University Medical Center, Leiden, Zuid Holland, Netherlands

🇳🇱

Amsterdam University Medical Center, Amsterdam, Netherlands

🇳🇱

Amphia Ziekenhuis, Breda, Netherlands

and more 8 locations

Quintuple Method for Treatment of Multiple Refractory Colorectal Liver Metastases

First Posted Date
2023-03-20
Last Posted Date
2023-03-20
Lead Sponsor
Liaoning Tumor Hospital & Institute
Target Recruit Count
100
Registration Number
NCT05774964
Locations
🇨🇳

Liaoning Tumor Hospital & Institute, Shenyang, Liaoning, China

Modulation of the Gut Microbiome With Pembrolizumab Following Chemotherapy in Resectable Pancreatic Cancer

First Posted Date
2022-07-18
Last Posted Date
2024-10-15
Lead Sponsor
Icahn School of Medicine at Mount Sinai
Target Recruit Count
25
Registration Number
NCT05462496
Locations
🇺🇸

Icahn School of Medicine at Mount Sinai, New York, New York, United States

Surgical Access Combined With Systematically Administered Antibiotics in the Treatment of Peri-implantitis

First Posted Date
2022-07-05
Last Posted Date
2024-07-18
Lead Sponsor
University of Guarulhos
Target Recruit Count
89
Registration Number
NCT05444218
Locations
🇧🇷

University of Guarulhos, Guarulhos, São Paulo, Brazil

Susceptibility-Guided Therapy for Helicobacter Pylori Infection Treatment

First Posted Date
2022-02-22
Last Posted Date
2022-03-18
Lead Sponsor
Shanghai Zhongshan Hospital
Target Recruit Count
388
Registration Number
NCT05250050
Locations
🇨🇳

Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, Shanghai, China

🇨🇳

Huashan Hospital, Fudan University, Shanghai, Shanghai, China

🇨🇳

Zhongshan Hospital, Fudan University, Shanghai, Shanghai, China

Efficacies of Hybrid and High-dose Dual Therapies for the First-line Anti-H Pylori Treatment

First Posted Date
2021-12-09
Last Posted Date
2022-07-20
Lead Sponsor
Chang Gung Memorial Hospital
Target Recruit Count
240
Registration Number
NCT05152004
Locations
🇨🇳

Chang Gung Memorial Hospital, Kaohsiung, Taiwan

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