• ARCALYST achieved remarkable growth with $417 million in 2024 net product revenue, representing a 79% year-over-year increase, with projected 2025 revenue between $560-580 million.
• Kiniksa plans to initiate Phase 2/3 clinical trial of KPL-387 for recurrent pericarditis in mid-2025, offering potential monthly subcutaneous dosing option for patients.
• Company announces strategic focus on cardiovascular indications while discontinuing abiprubart development in Sjögren's Disease, maintaining positive cash flow expectations.