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Fomepizole

Generic Name
Fomepizole
Brand Names
Antizol
Drug Type
Small Molecule
Chemical Formula
C4H6N2
CAS Number
7554-65-6
Unique Ingredient Identifier
83LCM6L2BY

Overview

Fomepizole is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. Fomepizole is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites.

Background

Fomepizole is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. Fomepizole is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites.

Indication

Antizol is indicated as an antidote for ethylene glycol (such as antifreeze) or methanol poisoning, or for use in suspected ethylene glycol or methanol ingestion, either alone or in combination with hemodialysis

Associated Conditions

  • Ethylene glycol poisoning
  • Methanol poisoning

FDA Approved Products

fomepizole
Manufacturer:American Regent, Inc.
Route:INTRAVENOUS
Strength:1 g in 1 mL
Approved: 2020/02/11
NDC:0517-0710
fomepizole
Manufacturer:American Regent, Inc.
Route:INTRAVENOUS
Strength:1 g in 1 mL
Approved: 2019/12/06
NDC:0517-0710
Fomepizole
Manufacturer:Gland Pharma Limited
Route:INTRAVENOUS
Strength:1 g in 1 mL
Approved: 2023/07/10
NDC:68083-510
Fomepizole
Manufacturer:Zydus Pharmaceuticals USA Inc.
Route:INTRAVENOUS
Strength:1 g in 1 mL
Approved: 2023/02/10
NDC:70710-1478
Fomepizole
Manufacturer:Sagent Pharmaceuticals
Route:INTRAVENOUS
Strength:1.5 g in 1.5 mL
Approved: 2023/12/19
NDC:25021-829

Singapore Approved Products

No Singapore products found for this drug

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