Deucravacitinib

Generic Name
Deucravacitinib
Brand Names
Sotyktu
Drug Type
Small Molecule
Chemical Formula
C20H22N8O3
CAS Number
1609392-27-9
Unique Ingredient Identifier
N0A21N6RAU
Background

Deucravacitinib is a novel oral selective tyrosine kinase 2 (TYK2) inhibitor. Unlike other Janus kinase 1/2/3 inhibitors that bind to the conserved active domain of these non-receptor tyrosine kinases, deucravacitinib binds to the regulatory domain of TYK2 with high selectivity to this therapeutic target. This selectivity towards TYK2 may lead to an improved...

Indication

Deucravacitinib is a tyrosine kinase 2 (TYK2) inhibitor indicated for the treatment of adults with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy. It is not recommended for use in combination with other potent immunosuppressants.

Associated Conditions
Severe Plaque psoriasis, Moderate Plaque psoriasis
Associated Therapies
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