Goserelin

Generic Name
Goserelin
Brand Names
Zoladex
Drug Type
Small Molecule
Chemical Formula
C59H84N18O14
CAS Number
65807-02-5
Unique Ingredient Identifier
0F65R8P09N
Background

Goserelin is a synthetic hormone. In men, it stops the production of the hormone testosterone, which may stimulate the growth of cancer cells. In women, goserelin decreases the production of the hormone estradiol (which may stimulate the growth of cancer cells) to levels similar to a postmenopausal state. When the medication is stopped, hormone levels return...

Indication

Goserelin is indicated for:

Associated Conditions
Abnormal Uterine Bleeding, Advanced Breast Cancer, Endometriosis, Advanced carcinoma of the prostate, Stage T2b carcinoma of the prostate, Stage T4 carcinoma of the prostate
Associated Therapies
Palliative Treatment

CMAB vs IMAB in Metastatic Prostate Cancer

Phase 4
Withdrawn
Conditions
First Posted Date
2005-11-18
Last Posted Date
2007-08-28
Lead Sponsor
AstraZeneca
Target Recruit Count
15
Registration Number
NCT00255268
Locations
🇲🇽

Research Site, Mexico City, Mexico

Prevention of Chemotherapy Induced Ovarian Failure With Goserelin in BC Patients (ZORO)

Phase 2
Completed
Conditions
First Posted Date
2005-09-20
Last Posted Date
2010-06-14
Lead Sponsor
German Breast Group
Target Recruit Count
62
Registration Number
NCT00196846
Locations
🇩🇪

Universitätsfrauenklinik, Rostock Universität, Rostock, Mecklenburg Vorpommern, Germany

Docetaxel, Estramustine and Short Term Androgen Withdrawal for Patients With a Rising PSA After Local Treatment

First Posted Date
2005-09-14
Last Posted Date
2018-06-25
Lead Sponsor
Dana-Farber Cancer Institute
Target Recruit Count
62
Registration Number
NCT00165399
Locations
🇺🇸

University of Massachusetts Memorial Medical Center-University Campus, Worcester, Massachusetts, United States

🇺🇸

Norris Cotton Cancer Center, Lebanon, New Hampshire, United States

🇺🇸

Dana-Farber Cancer Institute, Boston, Massachusetts, United States

and more 2 locations

Radiation Therapy With Androgen Suppression in Treating Patients With Prostate Cancer

Phase 2
Completed
Conditions
First Posted Date
2004-04-22
Last Posted Date
2023-08-18
Lead Sponsor
Alliance for Clinical Trials in Oncology
Target Recruit Count
180
Registration Number
NCT00002889
Locations
🇺🇸

University of Chicago Cancer Research Center, Chicago, Illinois, United States

🇺🇸

Duke Comprehensive Cancer Center, Durham, North Carolina, United States

🇺🇸

Dana-Farber Cancer Institute, Boston, Massachusetts, United States

and more 9 locations

Radiation Therapy With or Without Antiandrogen Therapy in Treating Patients With Stage I or Stage II Prostate Cancer

First Posted Date
2004-02-27
Last Posted Date
2018-06-14
Lead Sponsor
Radiation Therapy Oncology Group
Target Recruit Count
2028
Registration Number
NCT00002597
Locations
🇺🇸

New York Medical College, Valhalla, New York, United States

🇺🇸

Wilkes Barre General Hospital, Wilkes-Barre, Pennsylvania, United States

🇺🇸

University of Texas - MD Anderson Cancer Center, Houston, Texas, United States

and more 236 locations

Hormone Therapy With or Without Surgery or Radiation Therapy in Treating Patients With Prostate Cancer

First Posted Date
2003-01-27
Last Posted Date
2020-04-03
Lead Sponsor
NCIC Clinical Trials Group
Target Recruit Count
361
Registration Number
NCT00002633
Locations
🇨🇦

QEII Health Sciences Center, Halifax, Nova Scotia, Canada

🇨🇦

Juravinski Cancer Centre at Hamilton Health Sciences, Hamilton, Ontario, Canada

🇨🇦

Cancer Centre of Southeastern Ontario at Kingston, Kingston, Ontario, Canada

and more 12 locations

S0032, Combination Chemotherapy Plus Hormone Therapy in Treating Patients With Metastatic Prostate Cancer

First Posted Date
2003-01-27
Last Posted Date
2013-07-16
Lead Sponsor
SWOG Cancer Research Network
Target Recruit Count
41
Registration Number
NCT00028769
Locations
🇺🇸

USC/Norris Comprehensive Cancer Center and Hospital, Los Angeles, California, United States

🇺🇸

CCOP - Atlanta Regional, Atlanta, Georgia, United States

🇺🇸

CCOP - Central Illinois, Decatur, Illinois, United States

and more 88 locations

S9921, Hormone Therapy With or Without Mitoxantrone and Prednisone in Patients Who Have Undergone Radical Prostatectomy for Prostate Cancer

First Posted Date
2003-01-27
Last Posted Date
2022-12-30
Lead Sponsor
SWOG Cancer Research Network
Target Recruit Count
983
Registration Number
NCT00004124
Locations
🇺🇸

Cancer Care Center at Advocate Lutheran Hospital, Park Ridge, Illinois, United States

🇺🇸

Alta Bates Comprehensive Cancer Center, Berkeley, California, United States

🇺🇸

Bismarck Cancer Center, Bismarck, North Dakota, United States

and more 228 locations

Hormone Therapy in Treating Patients With Rising PSA Levels Following Radiation Therapy for Prostate Cancer

First Posted Date
2003-01-27
Last Posted Date
2021-06-23
Lead Sponsor
NCIC Clinical Trials Group
Target Recruit Count
1386
Registration Number
NCT00003653
Locations
🇨🇦

BCCA - Cancer Centre for the Southern Interior, Kelowna, British Columbia, Canada

🇨🇦

BCCA - Fraser Valley Cancer Centre, Surrey, British Columbia, Canada

🇨🇦

Clinical Research Unit at Vancouver Coastal, Vancouver, British Columbia, Canada

and more 26 locations

Thalidomide for the Treatment of Hormone-Dependent Prostate Cancer

First Posted Date
2000-02-21
Last Posted Date
2018-05-22
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
159
Registration Number
NCT00004635
Locations
🇺🇸

University of Minnesota, Minneapolis, Minnesota, United States

🇺🇸

Wayne State University Hutzel Hospital, Detroit, Michigan, United States

🇺🇸

University of Washington, Seattle, Washington, United States

and more 6 locations
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