Goserelin

Generic Name
Goserelin
Brand Names
Zoladex
Drug Type
Small Molecule
Chemical Formula
C59H84N18O14
CAS Number
65807-02-5
Unique Ingredient Identifier
0F65R8P09N
Background

Goserelin is a synthetic hormone. In men, it stops the production of the hormone testosterone, which may stimulate the growth of cancer cells. In women, goserelin decreases the production of the hormone estradiol (which may stimulate the growth of cancer cells) to levels similar to a postmenopausal state. When the medication is stopped, hormone levels return...

Indication

Goserelin is indicated for:

Associated Conditions
Abnormal Uterine Bleeding, Advanced Breast Cancer, Endometriosis, Advanced carcinoma of the prostate, Stage T2b carcinoma of the prostate, Stage T4 carcinoma of the prostate
Associated Therapies
Palliative Treatment

The Influence of Adjuvant Medical Treatment of Peritoneal Endometriosis on the Outcome of IVF. A Prospective Randomized Analysis.

Phase 4
Completed
Conditions
Interventions
First Posted Date
2012-09-11
Last Posted Date
2015-03-20
Lead Sponsor
AZ Jan Palfijn Gent
Target Recruit Count
120
Registration Number
NCT01682642
Locations
🇧🇪

AZ Jan Palfijn, Gent, Oost-vlaanderen, Belgium

Tecemotide (L-BLP25) in Prostate Cancer

First Posted Date
2011-12-21
Last Posted Date
2018-03-09
Lead Sponsor
EMD Serono
Target Recruit Count
28
Registration Number
NCT01496131
Locations
🇺🇸

Please Contact US Medical Information, Rockland, Massachusetts, United States

Ipilimumab + Androgen Depravation Therapy in Prostate Cancer

First Posted Date
2011-06-21
Last Posted Date
2023-09-29
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
30
Registration Number
NCT01377389
Locations
🇺🇸

University of Texas MD Anderson Cancer Center, Houston, Texas, United States

Fulvestrant (F)/Goserelin (G) vs Anastrozole (A)/G vs G for Premenopausal Women

First Posted Date
2010-12-24
Last Posted Date
2017-05-01
Lead Sponsor
Samsung Medical Center
Target Recruit Count
147
Registration Number
NCT01266213
Locations
🇰🇷

Samsung Medical Center, Seoul, Korea, Republic of

International,Multi-Center,Open Label,Randomized Study Assessing the Safety and Efficacy of a Monthly Dosing Regimen of Ozarelix Versus Goserelin Depot in Men With Prostate Cancer

Phase 2
Completed
Conditions
Interventions
First Posted Date
2010-12-03
Last Posted Date
2021-10-05
Lead Sponsor
Spectrum Pharmaceuticals, Inc
Target Recruit Count
203
Registration Number
NCT01252693
Locations
🇺🇸

Urology Clinics of North Texas, Dallas, Texas, United States

🇺🇸

The Urology Center of Colorado, Denver, Colorado, United States

🇺🇸

Urology San Antonio Research, San Antonio, Texas, United States

Docetaxel Followed by Radical Prostatectomy in Patients With High Risk Localized Prostate Cancer

First Posted Date
2010-12-01
Last Posted Date
2014-02-04
Lead Sponsor
Beth Israel Deaconess Medical Center
Target Recruit Count
28
Registration Number
NCT01250717
Locations
🇺🇸

Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States

Trial of MK-2206 + Endocrine Treatment in Patients With Hormone Receptor Positive Breast Cancer

First Posted Date
2010-11-15
Last Posted Date
2013-08-20
Lead Sponsor
Vanderbilt-Ingram Cancer Center
Registration Number
NCT01240941

MK-2206+Endocrine Therapy in Patients With Hormone Receptor-Positive Breast Cancer

First Posted Date
2010-11-15
Last Posted Date
2013-08-20
Lead Sponsor
Vanderbilt-Ingram Cancer Center
Registration Number
NCT01240928

Endocrine Therapy + OSI-906 With or Without Erlotinib for Hormone-Sensitive Metastatic Breast Cancer

First Posted Date
2010-09-20
Last Posted Date
2012-09-11
Lead Sponsor
Vanderbilt-Ingram Cancer Center
Target Recruit Count
11
Registration Number
NCT01205685
Locations
🇺🇸

Vanderbilt-Ingram Oncology Cool Springs, Franklin, Tennessee, United States

🇺🇸

Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, United States

🇺🇸

Vanderbilt One Hundre Oaks, Nashville, Tennessee, United States

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