Paroxetine

Generic Name
Paroxetine
Brand Names
Paxil, Pexeva
Drug Type
Small Molecule
Chemical Formula
C19H20FNO3
CAS Number
61869-08-7
Unique Ingredient Identifier
41VRH5220H
Background

Paroxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. It has a variety of uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and symptoms of menopause, among others. It was approved by the FDA in the early 1990s and marketed by SmithKline Beecham. A unique feature of this...

Indication

Paroxetine is indicated for the management of depression, obsessive-compulsive disorder, panic disorder, social anxiety disorder, generalized anxiety disorder, posttraumatic stress disorder. One form of paroxetine, commercially known as Brisdelle, is used to manage mild to moderate vasomotor symptoms of menopause. Off-label, paroxetine may be used for the tr...

Associated Conditions
Generalized Anxiety Disorder, Irritable Bowel Syndrome (IBS), Major Depressive Disorder (MDD), Obsessive Compulsive Disorder (OCD), Panic Disorder, Post Traumatic Stress Disorder (PTSD), Premature Ejaculation, Premenstrual Dysphoric Disorder (PMDD), Social Anxiety Disorder (SAD), Vasomotor Symptoms Associated With Menopause
Associated Therapies
-
Clinical Trials
Related News

Effect of Paroxetine on Smokers' Cardiovascular Response to Stress - 1

Not Applicable
Completed
Conditions
Tobacco Use Disorder
Interventions
Drug: Paroxetine
Drug: Placebo
First Posted Date
2005-09-22
Last Posted Date
2019-11-01
Lead Sponsor
University of Minnesota
Target Recruit Count
105
Registration Number
NCT00218439
Locations
🇺🇸

College of Pharmacy, Minneapolis, Minnesota, United States

Risperidone vs. Paroxetine for Panic Attacks

First Posted Date
2005-09-21
Last Posted Date
2012-10-22
Lead Sponsor
Beth Israel Medical Center
Target Recruit Count
90
Registration Number
NCT00206765
Locations
🇺🇸

Beth Israel Medical Center, New York, New York, United States

Paroxetine for the Treatment of Interferon Related Side Effects for Hepatitis C

First Posted Date
2005-09-21
Last Posted Date
2016-04-11
Lead Sponsor
Emory University
Target Recruit Count
60
Registration Number
NCT00209118

Efficacy of Paroxetine in the Prevention of Depressive Syndrome in Patients With Chronic Hepatitis C Treated by PEG-Interferon Alfa Plus Ribavirin

Phase 3
Completed
Conditions
Chronic Hepatitis C
First Posted Date
2005-09-20
Last Posted Date
2009-05-13
Lead Sponsor
French National Agency for Research on AIDS and Viral Hepatitis
Target Recruit Count
144
Registration Number
NCT00196664
Locations
🇫🇷

Service d'Hépato-gastroentérologie CHU de Nancy, Vandoeuvre, France

Prazosin vs Paroxetine in Combat Stress-Related Post-Traumatic Stress Disorder (PTSD) Nightmares & Sleep Disturbance

First Posted Date
2005-09-20
Last Posted Date
2018-07-10
Lead Sponsor
Seattle Institute for Biomedical and Clinical Research
Target Recruit Count
59
Registration Number
NCT00202449
Locations
🇺🇸

Madigan Army Medical Center, Fort Lewis, Washington, United States

🇺🇸

Walter Reed Army Medical Center, Washington, District of Columbia, United States

Comparison of LY686017 With a Marketed Drug in the Treatment of Social Anxiety Disorder

Phase 2
Completed
Conditions
Social Phobia
First Posted Date
2005-09-19
Last Posted Date
2007-02-13
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
185
Registration Number
NCT00191022
Locations
🇺🇸

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. test, West Allis, Wisconsin, United States

Study Comparing Venlafaxine vs. Paroxetine in Panic Disorder

Phase 3
Completed
Conditions
Panic Disorders
First Posted Date
2005-09-19
Last Posted Date
2010-04-02
Lead Sponsor
Wyeth is now a wholly owned subsidiary of Pfizer
Target Recruit Count
70
Registration Number
NCT00195598

Paroxetine in the Treatment of Chronic Primary Insomnia

Phase 4
Completed
Conditions
Primary Insomnia
Depression
First Posted Date
2005-09-15
Last Posted Date
2005-09-15
Lead Sponsor
University of Pittsburgh
Target Recruit Count
66
Registration Number
NCT00178048
Locations
🇺🇸

University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States

🇺🇸

University of Pittsubrgh Medical Center, Pittsburgh, Pennsylvania, United States

Sleep Deprivation Plus Paroxetine for Treating Major Depression in Elderly Individuals

Phase 4
Completed
Conditions
Depression
First Posted Date
2005-09-15
Last Posted Date
2013-08-02
Lead Sponsor
University of Pittsburgh
Target Recruit Count
158
Registration Number
NCT00178035
Locations
🇺🇸

University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States

Paroxetine and Interpersonal Psychotherapy for Maintaining Health and Well-being in Elderly Individuals With Depression

Phase 4
Completed
Conditions
Unipolar Depression
First Posted Date
2005-09-15
Last Posted Date
2013-08-02
Lead Sponsor
University of Pittsburgh
Target Recruit Count
225
Registration Number
NCT00178100
Locations
🇺🇸

University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States

© Copyright 2024. All Rights Reserved by MedPath
HomeTerms & ConditionsPrivacy Policy