MedPath

Chlordiazepoxide

Generic Name
Chlordiazepoxide
Brand Names
Chlorax, Librax
Drug Type
Small Molecule
Chemical Formula
C16H14ClN3O
CAS Number
58-25-3
Unique Ingredient Identifier
6RZ6XEZ3CR

Overview

An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.

Background

An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.

Indication

Chlordiazepoxide is indicated for the management of anxiety disorders or for the short-term relief of symptoms of anxiety, withdrawal symptoms of acute alcoholism, and preoperative apprehension and anxiety. In combination with amitriptyline, chlordiazepoxide is indicated for the treatment of moderate to severe depression. In combination with clidinium, chlordiazepoxide is indicated to control emotional and somatic factors in gastrointestinal disorders, and is used as adjunctive therapy in the treatment of peptic ulcer, irritable bowel syndrome and acute enterocolitis.

Associated Conditions

  • Alcohol Withdrawal Syndrome
  • Anxiety Disorders
  • Depression
  • Irritable Bowel Syndrome (IBS)
  • Peptic Ulcer Disease
  • Preoperative Anxiety
  • Acute Enterocolitis

FDA Approved Products

Chlordiazepoxide and Amitriptyline Hydrochloride
Manufacturer:Mylan Pharmaceuticals Inc.
Route:ORAL
Strength:5 mg in 1 1
Approved: 2024/02/15
NDC:0378-0211
Chlordiazepoxide and Amitriptyline Hydrochloride
Manufacturer:Micro Labs Limited
Route:ORAL
Strength:25 mg in 1 1
Approved: 2023/01/19
NDC:42571-303
Chlordiazepoxide and Amitriptyline Hydrochloride
Manufacturer:Mylan Pharmaceuticals Inc.
Route:ORAL
Strength:10 mg in 1 1
Approved: 2024/02/15
NDC:0378-0277
Chlordiazepoxide Hydrochloride and Clidinium Bromide
Manufacturer:Xiromed, LLC
Route:ORAL
Strength:5 mg in 1 1
Approved: 2021/03/31
NDC:70700-185
Chlordiazepoxide and Amitriptyline Hydrochloride
Manufacturer:Micro Labs Limited
Route:ORAL
Strength:12.5 mg in 1 1
Approved: 2023/01/19
NDC:42571-302

Singapore Approved Products

CHLOBAX TABLET
Manufacturer:BEACONS PHARMACEUTICALS PTE LTD
Form:TABLET, SUGAR COATED
Strength:5 mg
Online:Yes
Approved: 1996/04/19
Approval:SIN08651P
AA PHARMA CHLORAX CAPSULE
Manufacturer:APOTEX INC
Form:CAPSULE
Strength:5 mg
Online:Yes
Approved: 1989/06/07
Approval:SIN03049P
BENPINE TABLET 5 mg
Manufacturer:ATLANTIC LABORATORIES CORPN LTD
Form:TABLET, SUGAR COATED
Strength:5 mg
Online:Yes
Approved: 1988/06/20
Approval:SIN01907P

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