Vanillic acid

The FDA announced it will phase out requirements for animal testing of monoclonal antibodies and other drugs, citing the availability of "more effective, human-relevant methods" for safety evaluation.

Clinical trials at Veterans Affairs hospitals, including a promising cancer treatment study in Pittsburgh, have been suspended due to staffing shortages caused by the Department of Government Efficiency (DOGE) cuts.

A comprehensive study utilizing the National COVID Cohort Collaborative (N3C) database reveals that Paxlovid treatment within 5 days of COVID-19 diagnosis significantly reduces the risk of hospitalization by 39% and death by 61%. The study highlights the drug's effectiveness across different age groups and vaccination statuses, while also pointing out persistent racial and social disparities in treatment access.

A comprehensive analysis of over 114 million VA healthcare appointments shows 10.87% were canceled on the same day, with patient cancellations, no-shows, and clinic cancellations being the primary reasons.

A significant collaboration between the VA and FDA is set to evaluate the effectiveness of different blood thinners through a new head-to-head clinical trial, aiming to enhance patient care and treatment outcomes.