Overview
Barium sulfate is an inorganic compound with the chemical formula BaSO4 . Barium sulfate occurs in nature as the mineral barite. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield . This drug is used as a contrast agent in diagnostic x-ray procedures. Therapeutic advantages of barium sulfate in diagnostic procedures include both its low water solubility and high level of clearance from the body . Barium sulfate is ingested by mouth or administered rectally and combined with granules of effervescent bicarbonate to enhance distension of the GI tract, allowing for enhanced gastrointestinal tract visualization , .
Background
Barium sulfate is an inorganic compound with the chemical formula BaSO4 . Barium sulfate occurs in nature as the mineral barite. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield . This drug is used as a contrast agent in diagnostic x-ray procedures. Therapeutic advantages of barium sulfate in diagnostic procedures include both its low water solubility and high level of clearance from the body . Barium sulfate is ingested by mouth or administered rectally and combined with granules of effervescent bicarbonate to enhance distension of the GI tract, allowing for enhanced gastrointestinal tract visualization , .
Indication
Barium sulfate is a radiographic contrast agent indicated for use in computed tomography (CT) of the abdomen to delineate the gastrointestinal (GI) tract in adult and pediatric patients .
Associated Conditions
- Radiologic examination of the gastrointestinal tract
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|
No clinical trials found
No clinical trials found for this drug
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| Vizumax Diagnostics LLC | 71719-2040 | RECTAL | 960 mg in 1 g | 10/4/2021 | |
| E-Z-EM Canada Inc | 32909-750 | ORAL | 960 mg in 1 g | 4/13/2017 | |
| E-Z-EM Canada Inc | 32909-116 | ORAL | 400 mg in 1 mL | 10/9/2020 | |
| E-Z-EM Canada Inc | 32909-121 | ORAL | 400 mg in 1 mL | 10/25/2023 | |
| E-Z-EM Canada Inc | 32909-741 | ORAL | 20 mg in 1 mL | 10/12/2020 | |
| E-Z-EM Canada Inc | 32909-167 | ORAL, RECTAL | 1.05 g in 1 mL | 2/1/2021 | |
| E-Z-EM Canada Inc | 32909-186 | ORAL | 0.6 g in 1 mL | 10/15/2020 | |
| E-Z-EM Canada Inc | 32909-105 | ORAL | .81 g in 1 g | 4/30/2019 | |
| E-Z-EM Canada Inc | 32909-125 | ORAL | 400 mg in 1 mL | 10/15/2018 | |
| E-Z-EM Canada Inc | 32909-777 | ORAL | 20 mg in 1 mL | 10/12/2020 |
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No HSA approvals found for this drug. | |||||
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| Barium Sulfate(Type Ⅱ)for Suspension | 国药准字H13021328 | 化学药品 | 干混悬剂 | 12/21/2020 | |
| Barium Sulfate(Type Ⅱ)for Suspension | 国药准字H61023572 | 化学药品 | 口服混悬剂 | 11/20/2020 | |
| Barium Sulfate(Type Ⅱ)for Suspension | 国药准字H20056856 | 化学药品 | 干混悬剂 | 1/3/2020 | |
| Barium Sulfate(Type Ⅱ)for Suspension | 国药准字H20163181 | 化学药品 | 口服混悬剂 | 4/14/2021 | |
| Barium Sulfate (Type Ⅰ)for Suspension | 国药准字H44022542 | 化学药品 | 干混悬剂 | 4/10/2020 | |
| Barium Sulfate (Type Ⅰ)for Suspension | 国药准字H20056854 | 化学药品 | 干混悬剂 | 3/10/2020 | |
| Barium Sulfate (Type Ⅰ)for Suspension | 国药准字H61021957 | 化学药品 | 口服混悬剂 | 11/20/2020 | |
| Barium Sulfate (Type Ⅰ)for Suspension | 国药准字H20163180 | 化学药品 | 口服混悬剂 | 4/14/2021 |
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| No PPB approvals found for this drug. | |||||
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
|---|---|---|---|---|---|
| READI-CAT 2 barium sulfate 20.9mg/mL oral suspension bottle (reformulation) | 129553 | Medicine | A | 7/17/2006 | |
| Stool Marker | 121175 | Medicine | A | 8/8/2005 | |
| E-Z-HD BARIUM SULFATE POWDER FOR ORAL SUSPENSION | 205168 | Medicine | A | 1/23/2013 |