Stiripentol
- Generic Name
- Stiripentol
- Brand Names
- Diacomit
- Drug Type
- Small Molecule
- Chemical Formula
- C14H18O3
- CAS Number
- 49763-96-4
- Unique Ingredient Identifier
- R02XOT8V8I
- Background
Stiripentol is an antiepileptic agent that is an aromatic allylic alcohol drug, which makes it structurally unique from other antiepileptic drugs. The clinical development and marketing of stiripentol were first delayed due to the drug's potent inhibitory effects on hepatic cytochrome P450 (CYP) enzymes. However, its clinical efficacy as adjunctive therapy f...
- Indication
In the US, stiripentol is indicated for the treatment of seizures associated with Dravet syndrome in patients taking clobazam who are 6 months of age and older and weighing 7 kg or more. There are no clinical data to support the use of stiripentol as monotherapy in Dravet syndrome.
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- Associated Conditions
- Seizures, Refractory Grand mal Generalized tonic-clonic seizure
- Associated Therapies
- -
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