Vitamin K1
- Generic Name
- Vitamin K1
- Brand Names
- Aquamephyton, Infuvite, Infuvite Pediatric, Mephyton, Mvi Pediatric, Phytonadione
- Drug Type
- Small Molecule
- Chemical Formula
- C31H46O2
- CAS Number
- 84-80-0
- Unique Ingredient Identifier
- S5Z3U87QHF
- Background
Vitamin K1, also called phylloquinone or phytonadione, is a fat soluble vitamin. Phylloquinone is a cofactor of the enzyme γ-carboxylase, which modifies and activates precursors to coagulation factors II, VII, IX, and X. It is indicated in the treatment of coagulation disorders due to faulty formation of coagulation factors II, VII, IX, and X caused by defic...
- Indication
Oral phylloquinone is indicated to treat prothrombin deficiency caused by coumarin or indanedione derivatives; and hypoprothrombinemia secondary to antibacterial therapy, salicylates, or obstructive jaundice or biliary fistulas with concomitant bile salt administration.
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- Associated Conditions
- Coagulation Disorder, Hypoprothrombinemia, Hemorrhagic disease of the newborn
- Associated Therapies
- Vitamin supplementation
Daily Vitamin K in Patients on Warfarin With Unstable INRs
- Conditions
- First Posted Date
- 2006-02-06
- Last Posted Date
- 2010-01-12
- Lead Sponsor
- University of North Carolina, Chapel Hill
- Target Recruit Count
- 15
- Registration Number
- NCT00287313
- Locations
- 🇺🇸
University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States
Effect of Vitamin K on Age-Related Bone Loss and Vascular Calcification
- Conditions
- First Posted Date
- 2005-09-16
- Last Posted Date
- 2009-02-16
- Lead Sponsor
- National Institute on Aging (NIA)
- Target Recruit Count
- 452
- Registration Number
- NCT00183001
- Locations
- 🇺🇸
Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts, United States
Drug Development Updates
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