Pilocarpine

Generic Name: Pilocarpine

Brand Names: Betoptic Pilo, Isoptocarpine, Minims Pilocarpine Nitrate, Salagen, Vuity

Drug Type: Small Molecule

Chemical Formula: C_₁₁H_₁₆N_₂O_₂

CAS Number: 92-13-7

Unique Ingredient Identifier: 01MI4Q9DI3

Background: Pilocarpine is a cholinergic muscarinic receptor agonist.

Indication: Pilocarpine oral tablets are indicated for the treatment of dry mouth caused by Sjogren's Syndrome or radiotherapy for cancer of the head and neck.

Pilocarpine ophthalmic formulations are used to treat presbyopia in adults, reduce elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension, manage acute angle-closure glaucoma, prevent postoperative elevated IOP associated with laser surgery, and induce miosis.

Associated Conditions: Acute angle-closure glaucoma, Dry Mouth, Glaucoma, Closed-Angle, Increased Intra Ocular Pressure (IOP), Narrow-angle glaucoma, Ocular Hypertension, Open Angle Glaucoma (OAG), Presbyopia, Chronic open-angle glaucoma

Associated Therapies: -

Clinical Trials

Presbyopia Treatment Market Set to Reach New Heights with New Therapies and

Emerging therapies like LNZ100, Phentolamine Ophthalmic Solution 0.75%, and BRIMOCHOL PF are set to impact the presbyopia market (2024–2034). Presbyopia, an age-related condition affecting near vision, has ~325 million prevalent cases in 7MM, expected to grow at 1.1% CAGR. Treatments include corrective lenses, surgical procedures, and eye drops like VUITY and QLOSI. Market size is projected to reach ~USD 17 billion by 2034 with a 3.2% CAGR, driven by innovative therapies and rising incidence.

theprint.in

4 months ago

Eye drop's claim to replace glasses cost it the launch & sale nod. The controversy & safety concerns

CDSCO revoked Entod Pharmaceuticals' authorization to market PresVu eye drops, citing false claims and safety concerns around pilocarpine, the active ingredient.

Drug Development Updates

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