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Mometasone

Generic Name
Mometasone
Brand Names
Asmanex, Dulera, Elocom, Elocon, Nasonex, Ryaltris, Sinuva, Zenhale, Atectura Breezhaler, Bemrist Breezhaler
Drug Type
Small Molecule
Chemical Formula
C27H30Cl2O6
CAS Number
83919-23-7
Unique Ingredient Identifier
04201GDN4R

Overview

Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions. It has a glucocorticoid receptor binding affinity 22 times stronger than dexamethasone and higher than many other corticosteroids as well. Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different indications.

Background

Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions. It has a glucocorticoid receptor binding affinity 22 times stronger than dexamethasone and higher than many other corticosteroids as well. Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different indications.

Indication

Inhaled mometasone furoate is indicated for prophylaxis of asthma in patients ≥4 years. Applied topically as an ointment, mometasone furoate is indicated for symptomatic treatment of dermatitis and pruritis in patients ≥2 years. Mometasone furoate nasal spray is available both over-the-counter (OTC) and by prescription. The OTC nasal spray formulation of mometasone furoate is indicated for the treatment of upper respiratory allergic symptoms (e.g. rhinorrhea, sneezing) in patients ≥2 years of age. The prescription formulation is indicated for the treatment of chronic rhinosinusitis with nasal polyps in patients ≥18 year old and for the and prophylaxis of seasonal allergic rhinitis in patients ≥12 years old. It is also approved in combination with olopatadine for the symptomatic treatment of seasonal allergic rhinitis in patients ≥12 years.

Associated Conditions

  • Asthma
  • Chronic Rhinosinusitis Phenotype With Nasal Polyps (CRSwNP)
  • Dermatitis
  • Dermatitis, Eczematous caused by superficial Fungal skin infection
  • Moderate to Severe Plaque Psoriasis
  • Pruritus
  • Psoriasis
  • Psoriasis, Moderate to Severe
  • Seasonal Allergic Rhinitis
  • Seasonal Allergies
  • Skin Diseases, Eczematous
  • Skin Infections
  • Moderate, severe Seasonal Allergic Rhinitis
  • Ocular effects

FDA Approved Products

ASMANEX HFA
Manufacturer:Organon LLC
Route:RESPIRATORY (INHALATION)
Strength:50 ug in 1 1
Approved: 2021/06/01
NDC:78206-111
Mometasone Furoate
Manufacturer:Preferred Pharmaceuticals Inc.
Route:TOPICAL
Strength:1 mg in 1 g
Approved: 2023/11/14
NDC:68788-8548
Mometasone Furoate
Manufacturer:Glenmark Pharmaceuticals Inc., USA
Route:TOPICAL
Strength:1 mg in 1 mL
Approved: 2020/05/31
NDC:68462-385
Mometasone Furoate
Manufacturer:Proficient Rx LP
Route:TOPICAL
Strength:1 mg in 1 g
Approved: 2024/02/01
NDC:63187-288
Mometasone Furoate
Manufacturer:A-S Medication Solutions
Route:TOPICAL
Strength:1 mg in 1 g
Approved: 2023/02/17
NDC:50090-1633

Singapore Approved Products

MOMETASONE SANDOZ NASAL SPRAY 0.05%
Manufacturer:Lek Pharmaceuticals d.d.
Form:SPRAY, SUSPENSION
Strength:50ug per actuation
Online:Yes
Approved: 2017/09/07
Approval:SIN15328P
ELOMET LOTION 0.1%
Manufacturer:Delpharm Montréal Inc.
Form:LOTION
Strength:0.1%
Online:Yes
Approved: 1993/12/06
Approval:SIN07565P
MOMETASONE NTC NASAL SPRAY SUSPENSION 50 MCG/ACTUATION
Manufacturer:Mipharm S.p.A
Form:SPRAY, SUSPENSION
Strength:50mcg/actuation
Online:Yes
Approved: 2018/02/26
Approval:SIN15434P
ATECTURA BREEZHALER INHALATION POWDER, HARD CAPSULE 150 MCG /320 MCG
Manufacturer:Novartis Pharma Stein AG, Siegfried Barbera S.L. (Primary and Secondary Packager)
Form:POWDER, METERED
Strength:320 mcg
Online:Yes
Approved: 2021/04/07
Approval:SIN16147P
ATECTURA BREEZHALER INHALATION POWDER, HARD CAPSULE 150 MCG /160 MCG
Manufacturer:Novartis Pharma Stein AG, Siegfried Barbera S.L. (Primary and Secondary Packager)
Form:POWDER, METERED
Strength:160 mcg
Online:Yes
Approved: 2021/04/07
Approval:SIN16148P

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