Mometasone

Generic Name
Mometasone
Brand Names
Asmanex, Dulera, Elocom, Elocon, Nasonex, Ryaltris, Sinuva, Zenhale
Drug Type
Small Molecule
Chemical Formula
C27H30Cl2O6
CAS Number
83919-23-7
Unique Ingredient Identifier
04201GDN4R
Background

Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions. It has a glucocorticoid receptor binding affinity 22 times stronger than dexamethasone and higher than many other corticosteroids as well. Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its ...

Indication

Inhaled mometasone furoate is indicated for prophylaxis of asthma in patients ≥4 years. Applied topically as an ointment, mometasone furoate is indicated for symptomatic treatment of dermatitis and pruritis in patients ≥2 years.
...

Associated Conditions
Asthma, Chronic Rhinosinusitis Phenotype With Nasal Polyps (CRSwNP), Dermatitis, Dermatitis, Eczematous caused by superficial Fungal skin infection, Moderate to Severe Plaque Psoriasis, Pruritus, Psoriasis, Psoriasis, Moderate to Severe, Seasonal Allergic Rhinitis, Seasonal Allergies, Skin Diseases, Eczematous, Skin Infections, Moderate, severe Seasonal Allergic Rhinitis, Ocular effects
Associated Therapies
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Topical Simvastatin Versus Topical Steroid in Treatment of Alopecia Areata

Phase 4
Not yet recruiting
Conditions
First Posted Date
2024-05-06
Last Posted Date
2024-05-06
Lead Sponsor
Assiut University
Target Recruit Count
54
Registration Number
NCT06399783
Locations
🇪🇬

Assiut university, Assiut, Egypt

Study to Compare the Pharmacokinetics of Fixed-Dose Combination of Mometasone + Azelastine Nasal Spray to Mometasone and Azelastine Nasal Sprays in Adolescents and Young Adults With Seasonal Allergic Rhinitis

First Posted Date
2023-06-05
Last Posted Date
2023-09-28
Lead Sponsor
Sandoz
Target Recruit Count
38
Registration Number
NCT05887843
Locations
🇨🇦

Sandoz Investigational Site, Toronto, Ontario, Canada

Prospective, Randomized, Multinational, Multicenter, Double-blind, Placebo and Active Controlled Trial in 4 Parallel-groups of Patients Suffering From Seasonal Allergic Rhinitis

First Posted Date
2022-04-05
Last Posted Date
2023-07-11
Lead Sponsor
Sandoz
Target Recruit Count
669
Registration Number
NCT05311475
Locations
🇵🇱

Sandoz Investigative Site, Wrocław, Poland

Research on Underlying Causes of Long-term Use of Nasal Decongestants and the Structured Withdrawal of the Decongestant

Phase 4
Recruiting
Conditions
Interventions
First Posted Date
2021-05-24
Last Posted Date
2024-10-30
Lead Sponsor
University Hospital, Ghent
Target Recruit Count
135
Registration Number
NCT04898764
Locations
🇧🇪

Ghent University Hospital, Ghent, Belgium

Efficacy and Safety of Magnólia Nasal Gel in the Treatment of Allergic Rhinitis

First Posted Date
2020-12-17
Last Posted Date
2022-08-05
Lead Sponsor
EMS
Registration Number
NCT04670653

Topical Cream SNG100 for Treatment in Moderate Atopic Dermatitis Subjects.

First Posted Date
2020-11-04
Last Posted Date
2020-11-04
Lead Sponsor
Seanergy Dermatology Ltd.
Target Recruit Count
66
Registration Number
NCT04615962

Study to Compare the Pharmacokinetics of Mometasone Furoate Alone and in Combination With Indacaterol in Patients ≥ 6 to < 12 Years Old With Asthma

First Posted Date
2020-10-19
Last Posted Date
2023-10-13
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
24
Registration Number
NCT04589663
Locations
🇿🇦

Novartis Investigative Site, Cape Town, South Africa

Comparison of Methylprednisolone or Methotrexate in the Maintenance Treatment of Nasal Polyposis

First Posted Date
2020-08-31
Last Posted Date
2020-08-31
Lead Sponsor
Dokuz Eylul University
Target Recruit Count
41
Registration Number
NCT04532736
Locations
🇹🇷

Dokuz Eylul University School of Medicine, İzmir, General, Turkey

A Study to Assess the Therapeutic Effect and Safety of Adjunctive AKST4290 in Subjects With Bullous Pemphigoid

First Posted Date
2020-08-05
Last Posted Date
2023-09-14
Lead Sponsor
Alkahest, Inc.
Target Recruit Count
6
Registration Number
NCT04499235
Locations
🇩🇪

Universitätsklinikum Freiburg Klinik für Dermatologie und Venerologie, Freiburg, Germany

🇩🇪

Universitätsklinikum Carl Gustav Carus Dresden Klinik und Poliklinik für Dermatologie, Dresden, Germany

🇩🇪

Universitätsmedizin der Johannes Gutenberg-Universität Mainz Hautklinik Clinical Research Center (CRC), Mainz, Germany

and more 5 locations

Comparative Study:Topison (Mometasone Furoate) Versus Two Others Mometasone Furoates

Phase 4
Completed
Conditions
Interventions
First Posted Date
2020-02-17
Last Posted Date
2023-10-11
Lead Sponsor
Libbs Farmacêutica LTDA
Target Recruit Count
32
Registration Number
NCT04271007
Locations
🇧🇷

Dr Sérgio Sckalka, Osasco, São Paulo, Brazil

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