MedPath

Triclabendazole

Generic Name
Triclabendazole
Brand Names
Egaten
Drug Type
Small Molecule
Chemical Formula
C14H9Cl3N2OS
CAS Number
68786-66-3
Unique Ingredient Identifier
4784C8E03O

Overview

Triclabendazole, manufactured by Novartis pharmaceuticals, is an antihelminthic drug that was approved by the FDA in February 2019 for the treatment of fascioliasis in humans. Fascioliasis is a parasitic infection often caused by the helminth, Fasciola hepatica, which is also known as “the common liver fluke” or “the sheep liver fluke” or by Fasciola gigantica, another helminth. These parasites can infect humans following ingestion of larvae in contaminated water or food. Triclabendazole was previously used in the treatment of fascioliasis in livestock, but is now approved for human use. This drug is currently the only FDA-approved drug for individuals with fascioliasis, which affects 2.4 million people worldwide.

Background

Triclabendazole, manufactured by Novartis pharmaceuticals, is an antihelminthic drug that was approved by the FDA in February 2019 for the treatment of fascioliasis in humans. Fascioliasis is a parasitic infection often caused by the helminth, Fasciola hepatica, which is also known as “the common liver fluke” or “the sheep liver fluke” or by Fasciola gigantica, another helminth. These parasites can infect humans following ingestion of larvae in contaminated water or food. Triclabendazole was previously used in the treatment of fascioliasis in livestock, but is now approved for human use. This drug is currently the only FDA-approved drug for individuals with fascioliasis, which affects 2.4 million people worldwide.

Indication

This drug is indicated for the treatment of fascioliasis in patients aged 6 years old and above.

Associated Conditions

  • Fascioliasis

FDA Approved Products

EGATEN
Manufacturer:Novartis Pharmaceuticals Corporation
Route:ORAL
Strength:250 mg in 1 1
Approved: 2019/02/13
NDC:0078-0937

Singapore Approved Products

No Singapore products found for this drug

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