Overview
Ferric pyrophosphate is an iron replacement product. Free iron presents several side effects as it can catalyze free radical formation and lipid peroxidation as well as the presence of interactions of iron in plasma. The ferric ion is strongly complexed by pyrophosphate. It presents an increasing interest as this insoluble form can be milder in the gastrointestinal tract and present higher bioavailability.
Indication
Ferric pyrophosphate is intended to be indicated for the treatment of iron loss or iron deficiency as a formulation with a milder gastrointestinal effect. Iron deficiency appears when the dietary intake does not meet the body's requirement or when there is chronic external blood loss. During acute blood loss, body iron stores are sufficient for accelerated erythropoiesis and restoration of iron homeostasis. But when the altered homeostasis remains for weeks to months then some supplement is needed. Some causes of iron deficiency include ectoparasitism, endoparasitism, hematuria, epistaxis, hemorrhagic skin, coagulopathy, thrombocytopenia, thrombocytopathia and gastrointestinal hemorrhage.
Associated Conditions
- Dialysis Dependent Chronic Kidney Disease
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2009/03/24 | Phase 1 | Completed |
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| Bestmade Natural Products | 82969-3016 | ORAL | 6 [hp_X] in 6 [hp_X] | 1/22/2025 | |
| Bestmade Natural Products | 82969-3023 | ORAL | 6 [hp_X] in 6 [hp_X] | 3/23/2025 | |
| Bestmade Natural Products | 82969-3019 | ORAL | 6 [hp_X] in 6 [hp_X] | 1/22/2025 | |
| Bestmade Natural Products | 82969-3011 | ORAL | 6 [hp_X] in 6 [hp_X] | 1/22/2025 | |
| Bestmade Natural Products | 82969-3012 | ORAL | 6 [hp_X] in 6 [hp_X] | 1/22/2025 | |
| Bestmade Natural Products | 82969-3015 | ORAL | 6 [hp_X] in 6 [hp_X] | 1/22/2025 | |
| Bestmade Natural Products | 82969-3010 | ORAL | 6 [hp_X] in 6 [hp_X] | 1/22/2025 | |
| Bestmade Natural Products | 82969-3024 | ORAL | 6 [hp_X] in 6 [hp_X] | 1/22/2025 | |
| Bestmade Natural Products | 82969-3017 | ORAL | 6 [hp_X] in 6 [hp_X] | 1/22/2025 | |
| Bestmade Natural Products | 82969-3009 | ORAL | 6 [hp_X] in 6 [hp_X] | 1/22/2025 |
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No HSA approvals found for this drug. | |||||
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| No NMPA approvals found for this drug. | |||||
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| No PPB approvals found for this drug. | |||||
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
|---|---|---|---|---|---|
| Kids Multi | 329564 | Medicine | A | 2/6/2020 | |
| Multivitamin + Iron Liquid for Kids | 394200 | Medicine | A | 8/22/2022 | |
| Life Botanics Kids Iron Gummies | 484532 | Medicine | A | 3/28/2025 | |
| Schuessler Tissue Salts Insomnia Comb A | 120752 | Medicine | A | 7/21/2005 | |
| Mild Iron | 400950 | Medicine | A | 12/12/2022 | |
| Iron Mom | 488609 | Medicine | A | 5/13/2025 | |
| Brauer Kids Liquid Iron with Vitamin B | 444213 | Medicine | A | 3/22/2024 | |
| fussy essentials | 423903 | Medicine | A | 10/4/2023 | |
| Witsbb Iron Flash Melt | 485133 | Medicine | A | 4/3/2025 | |
| Appetite + | 462305 | Medicine | A | 9/17/2024 |
Health Canada Drug Approvals
Approved Product | Company | DIN | Dosage Form | Strength | Market Date |
|---|---|---|---|---|---|
| No Health Canada approvals found for this drug. | |||||
CIMA AEMPS Drug Approvals
Approved Product | Company | Registration Number | Pharmaceutical Form | Prescription Type | Status |
|---|---|---|---|---|---|
| No CIMA AEMPS (Spain) approvals found for this drug. | |||||
Philippines FDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Philippines FDA approvals found for this drug. | |||||
Saudi SFDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Saudi SFDA approvals found for this drug. | |||||
Malaysia NPRA Drug Approvals
Approved Product | Company | Registration Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Malaysia NPRA approvals found for this drug. | |||||
UK EMC Drug Information
Medicine Name | MA Holder | MA Number | Pharmaceutical Form | Active Ingredient | Authorization Date |
|---|---|---|---|---|---|
| No UK EMC drug information found for this drug. | |||||
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