乙苯妥英 (Peganone)

概览

Ethotoin is a hydantoin antiepileptic used to control tonic-clonic and complex partial seizures.

作用机制

The mechanism of action is probably very similar to that of phenytoin. The latter drug appears to stabilize rather than to raise the normal seizure threshold, and to prevent the spread of seizure activity rather than to abolish the primary focus of seizure discharges. Ethotoin inhibits nerve impulses in the motor cortex by lowering sodium ion influx, limiting tetanic stimulation.

适应症

For the control of tonic-clonic (grand mal) and complex partial (psychomotor) seizures.

• Complex Partial Seizure Disorder
• Generalized Tonic-Clonic Seizures