Insulin degludec

Generic Name
Insulin degludec
Brand Names
Ryzodeg, Tresiba, Xultophy
Drug Type
Biotech
Chemical Formula
-
CAS Number
844439-96-9
Unique Ingredient Identifier
54Q18076QB
Background

Insulin degludec is an ultra-long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the pancreas that promotes glucose metabolism. ...

Indication

Insulin degludec is indicated to improve glycemic control in patients 1 year of age and older with diabetes mellitus.

Associated Conditions
Diabetes Mellitus, Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus
Associated Therapies
-

A Trial Evaluating the Blood Glucose-lowering Effect of NN1250 in Subjects With Type 2 Diabetes

Phase 1
Completed
Conditions
Interventions
First Posted Date
2010-07-01
Last Posted Date
2017-01-20
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
49
Registration Number
NCT01154881
Locations
🇩🇪

Novo Nordisk Investigational Site, Neuss, Germany

A Trial Comparing the Effect of NN1250 After Different Routes of Injection in Healthy Subjects

Phase 1
Completed
Conditions
Interventions
First Posted Date
2010-06-25
Last Posted Date
2017-01-20
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
20
Registration Number
NCT01151072
Locations
🇩🇪

Novo Nordisk Investigational Site, Neuss, Germany

A Trial Investigating the Effect of NN1250 in Japanese Subjects With Type 1 Diabetes

First Posted Date
2010-06-03
Last Posted Date
2017-01-20
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
22
Registration Number
NCT01135927
Locations
🇯🇵

Novo Nordisk Investigational Site, Tokyo, Japan

Switching From Insulin Glargine to Insulin Degludec in Subjects With Type 2 Diabetes Mellitus (BEGIN™)

First Posted Date
2010-06-03
Last Posted Date
2016-01-22
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
143
Registration Number
NCT01135992
Locations
🇺🇸

Novo Nordisk Clinical Trial Call Center, Olympia, Washington, United States

A Trial Evaluating the Effect of NN1250 at Steady State Conditions in Subjects With Type 1 Diabetes

First Posted Date
2010-05-03
Last Posted Date
2017-10-09
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
66
Registration Number
NCT01114542
Locations
🇩🇪

Novo Nordisk Investigational Site, Neuss, Germany

Comparison of NN1250 With Insulin Glargine in Type 1 Diabetes

First Posted Date
2010-03-03
Last Posted Date
2017-02-09
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
493
Registration Number
NCT01079234
Locations
🇬🇧

Novo Nordisk Investigational Site, Welwyn Garden City, United Kingdom

Comparison of Two NN1250 Formulations in Subjects With Type 1 Diabetes

Phase 1
Completed
Conditions
Interventions
First Posted Date
2010-02-26
Last Posted Date
2017-01-23
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
33
Registration Number
NCT01076634
Locations
🇦🇹

Novo Nordisk Investigational Site, Graz, Austria

Comparison of NN1250 With Insulin Glargine in Subjects With Type 2 Diabetes

First Posted Date
2010-02-26
Last Posted Date
2017-03-06
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
467
Registration Number
NCT01076647
Locations
🇷🇴

Novo Nordisk Investigational Site, Satu Mare, Romania

Comparison of NN1250 Plus Insulin Aspart With Insulin Detemir Plus Insulin Aspart in Type 1 Diabetes

First Posted Date
2010-02-24
Last Posted Date
2017-03-06
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
456
Registration Number
NCT01074268
Locations
🇬🇧

Novo Nordisk Investigational Site, Wirral, Merseyside, United Kingdom

Comparison of NN1250 With Insulin Glargine in Subjects With Type 2 Diabetes

First Posted Date
2010-02-15
Last Posted Date
2017-03-06
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
460
Registration Number
NCT01068665
Locations
🇬🇧

Novo Nordisk Investigational Site, Wrexham, United Kingdom

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