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A P2Y12 inhibitor and platelet aggregation inhibitor.
A P2Y12 inhibitor and platelet aggregation inhibitor.
PRT060128 is a specific, reversible ADP receptor antagonist that binds to the P2Y12 receptor on platelets. PRT06128 prevents binding of adenosine diphosphate (ADP) to its platelet receptor, impairing the ADP-mediated activation of the glycoprotein GPIIb/IIIa complex, a key step in the coagulation cascade. PRT060128 likely has a similar mechanism of action to clopidogrel.
Investigated for use/treatment in cardiovascular disorders and myocardial infarction.
每项发明一条,涵盖美国、欧洲、PCT 与中国的同族专利。