Vericiguat
- Generic Name
- Vericiguat
- Brand Names
- Verquvo
- Drug Type
- Small Molecule
- Chemical Formula
- C19H16F2N8O2
- CAS Number
- 1350653-20-1
- Unique Ingredient Identifier
- LV66ADM269
- Background
Vericiguat is a direct stimulator of soluble guanylate cyclase (sGC) used in the management of systolic heart failure to reduce mortality and hospitalizations. A key component of the NO-sGC-cGMP signaling pathway that helps to regulate the cardiovascular system, sGC enzymes are intracellular enzymes found in vascular smooth muscle cells (amongst other cell t...
- Indication
适用于近期心力衰竭失代偿经静脉治疗后病情稳定的射血分数降低（射血分数<45%）的症状性慢性心力衰竭成人患者，以降低发生心力衰竭住院或需要急诊静脉利尿剂治疗的风险。
- Associated Conditions
- Cardiovascular Mortality, Heart Failure Hospitalization
- Associated Therapies
- -
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