Mesalazine
- Generic Name
- Mesalazine
- Brand Names
- Apriso, Asacol, Canasa, Delzicol, Lialda, Mezavant, Pentasa, Rowasa, Salofalk, Zaldyon
- Drug Type
- Small Molecule
- Chemical Formula
- C7H7NO3
- CAS Number
- 89-57-6
- Unique Ingredient Identifier
- 4Q81I59GXC
- Background
An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory drugs like acetylsalicylic acid, which is active in inflammatory bowel disease . Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stabil...
- Indication
适用于溃疡性结肠炎和克罗恩病（Crohn病）。
- Associated Conditions
- Acute Ulcerative Colitis, Crohn's Disease Relapse, Crohn's Ileocolitis, Mild to Moderate Ulcerative Colitis, Proctitis, Proctitis, Ulcerative, Proctosigmoiditis, Ulcerative Colitis in Remission, Mild Ulcerative Colitis, Mild to moderate distal ulcerative colitis, Moderate Ulcerative colitis
- Associated Therapies
- -
Atorvastatin Efficacy and Safety in Patients With Ulcerative Colitis
- Conditions
- Interventions
- First Posted Date
- 2022-10-05
- Last Posted Date
- 2024-04-10
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 44
- Registration Number
- NCT05567068
- Locations
- 🇪🇬
Faculty of Medicine, Mansoura University, Mansoura, Egypt
Effectiveness of Fecal Microbiota Transplantation as add-on Therapy in Mild-to-moderate Ulcerative Colitis
- Conditions
- Interventions
- First Posted Date
- 2022-09-13
- Last Posted Date
- 2022-09-13
- Lead Sponsor
- Bogomolets National Medical University
- Target Recruit Count
- 53
- Registration Number
- NCT05538026
- Locations
- 🇺🇦
Bogomolets National Medical University, Kyiv, Ukraine
🇺🇦Ukrainian Research and Practical Centre of Endocrine Surgery, Transplantation of Endocrine Organs and Tissues of the Ministry of Health of Ukraine, Kyiv, Ukraine
A Study to Assess Adverse Events and Change in Disease Condition of Mesalamine Capsules in Children Aged 5 to 17 Years With Ulcerative Colitis
- Conditions
- Interventions
- First Posted Date
- 2022-04-07
- Last Posted Date
- 2024-03-29
- Lead Sponsor
- AbbVie
- Target Recruit Count
- 80
- Registration Number
- NCT05316220
- Locations
- 🇺🇸
Angel Kids Pediatrics /ID# 244874, Jacksonville, Florida, United States
🇺🇸UH Cleveland Medical Center /ID# 243375, Cleveland, Ohio, United States
🇺🇸Treken Primary Care /ID# 241302, Atlanta, Georgia, United States
Efficacy of Mesalazine Combined With Biologics in the Treatment of Moderate to Severe Ulcerative Colitis
- Conditions
- Interventions
- First Posted Date
- 2022-01-25
- Last Posted Date
- 2023-12-05
- Target Recruit Count
- 438
- Registration Number
- NCT05205603
- Locations
- 🇨🇳
People's Hospital of Chongqing, Chongqing, Chongqing, China
🇨🇳Shunde Hospital of Southern Medical University, Guangzhou, Guangdong, China
🇨🇳The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China
Administration of Hydroxychloroquine (Plaquenil) to African Americans and Hispanics for the Treatment of Mild to Severe Ulcerative Colitis
- Conditions
- Interventions
- First Posted Date
- 2021-11-12
- Last Posted Date
- 2024-03-04
- Lead Sponsor
- Icahn School of Medicine at Mount Sinai
- Target Recruit Count
- 20
- Registration Number
- NCT05119140
- Locations
- 🇺🇸
Icahn School of Medicine at Mount Sinai/Mount Sinai Hospital, New York, New York, United States
🇺🇸Emory University School of Medicine, Atlanta, Georgia, United States
Mesalamine for Colorectal Cancer Prevention Program in Lynch Syndrome
- Conditions
- Interventions
- First Posted Date
- 2021-06-09
- Last Posted Date
- 2024-12-17
- Lead Sponsor
- Ann-Sofie Backman
- Target Recruit Count
- 150
- Registration Number
- NCT04920149
- Locations
- 🇩🇰
Aalborg University Hospital, Aalborg, Denmark
🇸🇪Ersta Hospital/Ersta Diakoni, Stockholm, Sweden
🇩🇰Hvidovre Hospital, Hvidovre, Denmark
Adherence of a 1.600 mg Single Tablet 5-ASA Treatment of Ulcerative Colitis
- First Posted Date
- 2019-10-21
- Last Posted Date
- 2023-09-26
- Lead Sponsor
- Flemming Bendtsen
- Target Recruit Count
- 200
- Registration Number
- NCT04133194
- Locations
- 🇩🇰
Copenhagen University Hospital Hvidovre, Hvidovre, Denmark
The Safety and Efficacy of TET Enema in the Treatment of UC
- Conditions
- Interventions
- First Posted Date
- 2019-04-16
- Last Posted Date
- 2019-05-15
- Target Recruit Count
- 75
- Registration Number
- NCT03917095
- Locations
- 🇨🇳
Medical Center for Digestive Diseases, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China
PRObiotic VSL#3® for Maintenance of Clinical and Endoscopic REMission in Ulcerative Colitis
- Conditions
- Interventions
- First Posted Date
- 2018-01-30
- Last Posted Date
- 2020-01-18
- Lead Sponsor
- VSL Pharmaceuticals
- Target Recruit Count
- 14
- Registration Number
- NCT03415711
- Locations
- 🇮🇹
Istituto di Medicina Interna CIC Columbus Policlinico Universitario Agostino Gemelli Università Cattolica del Sacro Cuore, Roma, Italy
Mesalazine With Hydrocortisone Sodium Succinate Enema for 4-Week Treatment in Patients With Ulcerative Colitis
- First Posted Date
- 2017-04-12
- Last Posted Date
- 2017-04-12
- Lead Sponsor
- Xijing Hospital of Digestive Diseases
- Target Recruit Count
- 528
- Registration Number
- NCT03110198
- Locations
- 🇨🇳
Xijing Digestive Disease, Xi'an, Shaanxi, China
Drug Development Updates
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