• AstraZeneca and Eli Lilly have formed a strategic partnership to develop AZD3293, a promising oral BACE inhibitor for early Alzheimer's disease, with Lilly contributing $500 million in milestone payments.
• The collaboration combines AstraZeneca's innovative drug development capabilities with Lilly's 25-year expertise in Alzheimer's research, aiming to accelerate the development of a potential disease-modifying treatment.
• BACE inhibition represents a promising therapeutic approach targeting amyloid plaque formation, offering hope where previous Alzheimer's treatments have failed.