Botulinum toxin type A

Generic Name: Botulinum toxin type A

Brand Names: Botox, Botox Cosmetic, Dysport, Jeuveau, Xeomin, Nuceiva

Drug Type: Biotech

Chemical Formula: -

CAS Number: 93384-43-1

Unique Ingredient Identifier: 0A6JH35GMQ

Background: In 2002, botulinum toxin A, also known as onabotulinumtoxinA or Botox, was the first type A botulism toxin to be introduced into the market for cosmetic use. With a wide variety of applications and favourable safety profile, Botulinum toxin A injection is a minimally invasive and promising treatment for cosmetic imperfections, muscle spasms, and other condit...

Indication: Botulinum toxin A is indicated for a variety of conditions, depending on the preparations. Cosmetically, it is used for the treatment of facial fine lines and wrinkles, specifically for upper facial rhytides, including forehead, lateral canthus, and glabellar lines.
...

Associated Conditions: Bladder pain, Blepharospasm, Cervical Dystonia, Chronic Migraine, Diabetic Neuropathies, Epicondylitis, Equinus deformity of foot, acquired, Facial Skin Wrinkles, Glabellar Frown Lines (GL), Lower Limb Spasticity, Myofascial Pain Syndrome, Neurogenic Detrusor Overactivity, Neurogenic Thoracic Outlet Syndrome, Overactive Bladder Syndrome (OABS), Post Stroke Pain, Postherpetic Neuralgia, Sialorrhea, Spasticity, Spinal Cord Injuries, Strabismus, TMJ Disorders, Trigeminal Neuralgia (TN), Upper Limb Spasticity, Urinary Incontinence (UI), Hypertonicity disorders of the 7th nerve, Moderate Glabellar Frown Lines (GL), Severe Glabellar Frown Lines (GL), Severe axillary hyperhidrosis

Associated Therapies: -

Clinical Trials

Masseter Myofascial Pain Relief Following an Intra-muscular Injection With Botulinum Toxin Type A.

Phase 2

Conditions: Myofascial Pain
Myalgia

Interventions: Other: saline solution
Drug: Botulinum toxin type A

First Posted Date: 2020-06-11

Last Posted Date: 2020-06-11

Lead Sponsor: Region Örebro County

Target Recruit Count: 48

Registration Number: NCT04426123

Effect of Video Game-assisted and BoNT-A Injection Therapy on Spasticity, Activity and Participation in CP Patients

Not Applicable

Conditions: Cerebral Palsy, Spastic

Interventions: Drug: IncobotulinumtoxinA
Device: Video game

First Posted Date: 2020-02-28

Last Posted Date: 2020-02-28

Lead Sponsor: Sunnaas Rehabilitation Hospital

Target Recruit Count: 25

Registration Number: NCT04290169

A Comparative Study of Botulinum Neurotoxin Type A in Treatment of Moderate to Severe Glabellar Frown Lines

Phase 1

Completed

Conditions: Glabellar Frown Lines

Interventions: Drug: Botulinum toxin type A

First Posted Date: 2020-02-24

Last Posted Date: 2020-07-09

Lead Sponsor: ATGC Co., Ltd.

Target Recruit Count: 60

Registration Number: NCT04281095

Locations: 🇰🇷
Nowon Eulji Medical Center, Seoul, Korea, Republic of

Botulinum Toxin Type A for Foot Dystonia-associated Pain in Parkinson's Disease

Phase 2

Conditions: Dystonia Disorder
Parkinson Disease

Interventions: Drug: Placebo
Drug: Botulinum toxin type A

First Posted Date: 2020-02-20

Last Posted Date: 2022-05-17

Lead Sponsor: University of Calgary

Target Recruit Count: 40

Registration Number: NCT04277247

Locations: 🇨🇦
Movement Disorder Program, Foothills Medical Center, Alberta Health Services, Calgary, Alberta, Canada

Intra-gastric Fundal and Body Injection of Botulinum Toxin A for Weight Loss, a Randomized Controlled Trial

Phase 2

Conditions: Obesity
Weight Loss

Interventions: Drug: Botulinum toxin type A
Behavioral: Weight Management Program

First Posted Date: 2020-02-18

Last Posted Date: 2020-02-18

Lead Sponsor: Tan Tock Seng Hospital

Target Recruit Count: 18

Registration Number: NCT04274608

Locations: 🇸🇬
Tan Tock Seng Hospital, Singapore, Singapore

Botulinum Toxin Type A Blockade of the Sphenopalatine Ganglion in Treatment-refractory Chronic Migraine

Phase 3

Recruiting

Conditions: Migraine Disorders

Interventions: Drug: placebo
Drug: Botulinum toxin type A

First Posted Date: 2019-08-28

Last Posted Date: 2023-12-15

Lead Sponsor: St. Olavs Hospital

Target Recruit Count: 170

Registration Number: NCT04069897

Locations: 🇳🇴
Nevroklinikken Universitetet i Oslo, Oslo Universitetssykehus HF, Oslo, Norway
🇳🇴
Haukeland University Hospital, department of Neurology, Bergen, Norway
🇳🇴
Nordland Hospital, department of Neurology, Bodø, Norway

and more 1 locations