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Aprocitentan

Generic Name
Aprocitentan
Brand Names
Jeraygo
Drug Type
Small Molecule
Chemical Formula
C16H14Br2N6O4S
CAS Number
1103522-45-7
Unique Ingredient Identifier
MZI81HV01P
Background

Aprocitentan is under investigation in clinical trial NCT03541174 (A Research Study to Show the Effect of Aprocitentan in the Treatment of Difficult to Control (Resistant) High Blood Pressure (Hypertension) and Find Out More About Its Safety).

A Study to Investigate the Effect of ACT-132577 on the Pharmacokinetics of Midazolam and 1-hydroxy Midazolam in Healthy Male Subjects

Phase 1
Completed
Conditions
Healthy Subjects
Interventions
Drug: Midalozam
First Posted Date
2016-07-22
Last Posted Date
2022-11-29
Lead Sponsor
Idorsia Pharmaceuticals Ltd.
Target Recruit Count
20
Registration Number
NCT02841761
Locations
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Investigator Site, Newark, New Jersey, United States

Clinical Study to Assess Body Fluid Homeostasis After Administration of ACT-132577 in Healthy Subjects

Phase 1
Completed
Conditions
Healthy Subjects
Interventions
Other: Placebo
First Posted Date
2016-03-15
Last Posted Date
2022-11-29
Lead Sponsor
Idorsia Pharmaceuticals Ltd.
Target Recruit Count
24
Registration Number
NCT02708004
Locations
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Investigator Site Lausanne, Lausanne, Switzerland

Dose-finding Study With ACT-132577 (Aprocitentan) in Participants With Essential Hypertension

First Posted Date
2015-11-13
Last Posted Date
2022-11-23
Lead Sponsor
Idorsia Pharmaceuticals Ltd.
Target Recruit Count
1659
Registration Number
NCT02603809
Locations
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LCC Medical Research Institute, Miami, Florida, United States

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Allied Biomedical Research Institute, INC, Miami, Florida, United States

๐Ÿ‡บ๐Ÿ‡ธ

Midwest Institute for Clinical Research, Indianapolis, Indiana, United States

and more 83 locations
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