Overview
Curcumin, also known as diferuloylmethane, is an active component in the golden spice turmeric (Curcuma longa) and in Curcuma xanthorrhiza oil. It is a highly pleiotropic molecule that exhibits antibacterial, anti-inflammatory, hypoglycemic, antioxidant, wound-healing, and antimicrobial activities . Due to these properties, curcumin has been investigated for the treatment and supportive care of clinical conditions including proteinuria, breast cancer, multiple myeloma, depression, and Non Small Cell Lung Cancer (NSCLC). Despite proven efficacy against numerous experimental models, poor bioavailability due to poor absorption, rapid metabolism, and rapid systemic elimination have been shown to limit the therapeutic efficacy of curcumin . Curcumin is under investigation for the treatment and supportive care of various clinical conditions including mucositis, rectal cancer, prostate cancer, chronic schizophrenia, and Mild Cognitive Impairment (MCI) .
Indication
No approved therapeutic indications.
Associated Conditions
No associated conditions information available.
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2025/03/20 | Phase 4 | Not yet recruiting | Erzincan Military Hospital | ||
2025/01/06 | Phase 3 | Not yet recruiting | Services Institute of Medical Sciences, Pakistan | ||
2024/09/20 | Phase 3 | Completed | Shaymaa Hussein Rafat Kotb | ||
2024/06/24 | Phase 2 | Not yet recruiting | |||
2024/04/24 | Phase 3 | Recruiting | |||
2024/04/11 | Phase 1 | ENROLLING_BY_INVITATION | Brent DeGeorge | ||
2024/04/02 | Phase 2 | Active, not recruiting | |||
2024/02/28 | Phase 2 | Completed | |||
2023/09/21 | Phase 1 | Completed | |||
2023/08/08 | Not Applicable | Completed |
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| No FDA approvals found for this drug. | |||||
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No HSA approvals found for this drug. | |||||
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| No NMPA approvals found for this drug. | |||||
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| No PPB approvals found for this drug. | |||||
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
|---|---|---|---|---|---|
| Meriva Curcumin | 276665 | Medicine | A | 6/16/2016 | |
| USANA HealthPak | 350153 | Medicine | A | 11/30/2020 | |
| Pain Relief Cream | 372433 | Medicine | A | 8/9/2021 | |
| METAGENICS INFLAGESIC | 387454 | Medicine | A | 4/26/2022 | |
| JoinTQ | 384091 | Medicine | A | 2/16/2022 | |
| My Alai™ Multisystem Support | 408964 | Medicine | A | 5/15/2023 | |
| Swisse Ultiboost Curcumin | 273666 | Medicine | A | 3/31/2016 | |
| Cellgevity | 294661 | Max Health & Living Australia Pty Ltd | Medicine | A | 10/5/2017 |
| BounceBack | 427921 | Mannatech Australia Pty Ltd | Medicine | A | 11/15/2023 |
| Caruso's Turmeric | 286551 | Medicine | A | 3/9/2017 |
Health Canada Drug Approvals
Approved Product | Company | DIN | Dosage Form | Strength | Market Date |
|---|---|---|---|---|---|
| No Health Canada approvals found for this drug. | |||||
CIMA AEMPS Drug Approvals
Approved Product | Company | Registration Number | Pharmaceutical Form | Prescription Type | Status |
|---|---|---|---|---|---|
| No CIMA AEMPS (Spain) approvals found for this drug. | |||||
Philippines FDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Philippines FDA approvals found for this drug. | |||||
Saudi SFDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Saudi SFDA approvals found for this drug. | |||||
Malaysia NPRA Drug Approvals
Approved Product | Company | Registration Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Malaysia NPRA approvals found for this drug. | |||||
UK EMC Drug Information
Medicine Name | MA Holder | MA Number | Pharmaceutical Form | Active Ingredient | Authorization Date |
|---|---|---|---|---|---|
| No UK EMC drug information found for this drug. | |||||
Help Us Improve
Your feedback helps us provide better drug information and insights.