Curcumin

Generic Name
Curcumin
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C21H20O6
CAS Number
458-37-7
Unique Ingredient Identifier
IT942ZTH98
Background

Curcumin, also known as diferuloylmethane, is an active component in the golden spice turmeric (Curcuma longa) and in Curcuma xanthorrhiza oil. It is a highly pleiotropic molecule that exhibits antibacterial, anti-inflammatory, hypoglycemic, antioxidant, wound-healing, and antimicrobial activities . Due to these properties, curcumin has been investigated for...

Indication

No approved therapeutic indications.

Associated Conditions
-
Associated Therapies
-

Trial of Curcumin to Prevent Progression of Low-risk Prostate Cancer Under Active Surveillance

Phase 3
Recruiting
Conditions
Interventions
First Posted Date
2018-12-10
Last Posted Date
2024-12-13
Lead Sponsor
University of Texas Southwestern Medical Center
Target Recruit Count
291
Registration Number
NCT03769766
Locations
🇺🇸

UT Southwestern Medical Center, Dallas, Texas, United States

Curcumin and Vascular and Cognitive Function in Patients With Chronic Kidney Disease

First Posted Date
2017-07-21
Last Posted Date
2024-10-08
Lead Sponsor
Diana Jalal
Target Recruit Count
94
Registration Number
NCT03223883
Locations
🇺🇸

University of Iowa, Iowa City, Iowa, United States

Curcumin and Function in Older Adults

First Posted Date
2017-03-21
Last Posted Date
2022-07-26
Lead Sponsor
University of Florida
Target Recruit Count
17
Registration Number
NCT03085680
Locations
🇺🇸

University of Florida, Gainesville, Florida, United States

"Curcumin" in Combination With Chemotherapy in Advanced Breast Cancer

First Posted Date
2017-03-08
Last Posted Date
2019-11-27
Lead Sponsor
National Center of Oncology, Armenia
Target Recruit Count
150
Registration Number
NCT03072992
Locations
🇦🇲

National Center of Oncology, Yerevan, Armenia

A Study Evaluating the Safety and Efficacy of Curcumin in Patients With Primary Sclerosing Cholangitis (PSC)

Phase 1
Completed
Conditions
Interventions
First Posted Date
2016-11-30
Last Posted Date
2020-01-18
Lead Sponsor
John E. Eaton
Target Recruit Count
15
Registration Number
NCT02978339
Locations
🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

Topical Curcumin for Precancer Cervical Lesions

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2016-10-26
Last Posted Date
2024-10-29
Lead Sponsor
Lisa Flowers
Target Recruit Count
7
Registration Number
NCT02944578
Locations
🇺🇸

Grady Memorial Hospital, Atlanta, Georgia, United States

🇺🇸

Grady Hospital - Ponce De Leon Clinic, Atlanta, Georgia, United States

Glutathione vs. Curcumin Clinical Trial

First Posted Date
2016-07-28
Last Posted Date
2020-01-29
Lead Sponsor
South Florida Veterans Affairs Foundation for Research and Education
Target Recruit Count
75
Registration Number
NCT02848417
Locations
🇺🇸

Miami VA Center, Miami, Florida, United States

Curcumin in Preventing Gastric Cancer in Patients With Chronic Atrophic Gastritis or Gastric Intestinal Metaplasia

First Posted Date
2016-05-26
Last Posted Date
2024-11-12
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
50
Registration Number
NCT02782949
Locations
🇭🇳

Hospital Regional de Occidente, Santa Rosa De Copan, Honduras

🇵🇷

University of Puerto Rico, San Juan, Puerto Rico

Nanocurcumin for Prostate Cancer Patients Undergoing Radiotherapy (RT)

First Posted Date
2016-03-31
Last Posted Date
2017-10-12
Lead Sponsor
Shahid Beheshti University of Medical Sciences
Target Recruit Count
64
Registration Number
NCT02724618
Locations
🇮🇷

Shohada-e-Tajrish Medical Center, Tehran, Iran, Islamic Republic of

Curcumin in Combination With 5FU for Colon Cancer

First Posted Date
2016-03-31
Last Posted Date
2020-01-18
Lead Sponsor
Baylor Research Institute
Target Recruit Count
13
Registration Number
NCT02724202
Locations
🇺🇸

Baylor Charles A. Sammons Cancer Center, Dallas, Texas, United States

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