Omeprazole
- Generic Name
- Omeprazole
- Brand Names
- Konvomep, Losec, Omeclamox, Omesec, Previdolrx Analgesic Pak, Prilosec, Talicia, Yosprala, Zegerid, Zegerid Reformulated Aug 2006, Zegerid With Magnesium Hydroxide
- Drug Type
- Small Molecule
- Chemical Formula
- C17H19N3O3S
- CAS Number
- 73590-58-6
- Unique Ingredient Identifier
- KG60484QX9
- Background
Originally approved by the FDA in 1989, omeprazole is a proton-pump inhibitor, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid. This drug was the first clinical useful drug in its class, and its approva...
- Indication
Omeprazole, according to the FDA label is a proton pump inhibitor (PPI) used for the following purposes:
• Treatment of active duodenal ulcer in adults
• Eradication of Helicobacter pylori to reduce the risk of duodenal ulcer
recurrence in adults
• Treatment of active benign gastric ulcer in adults
...
- Associated Conditions
- Ankylosing Spondylitis (AS), Duodenal Ulcer, Erosive Esophagitis, Gastric Ulcer, Gastro-esophageal Reflux Disease (GERD), Healing, Heartburn, Helicobacter Pylori Infection, Osteoarthritis (OA), Rheumatoid Arthritis, Upper GI Bleeding, Zollinger-Ellison Syndrome, Benign, active Gastric Ulcer, Develop NSAID-induced gastric ulcers, Hypersecretory conditions, Multiple endocrine adenomas
- Associated Therapies
- -
Omeprazole and Reflux Disease - Improvement of Clinical Outcome by Genotype-adjusted Dosing
- First Posted Date
- 2007-10-01
- Last Posted Date
- 2014-02-25
- Lead Sponsor
- Matthias Schwab
- Target Recruit Count
- 68
- Registration Number
- NCT00537732
- Locations
- 🇩🇪
Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Baden-Württemberg, Germany
Optimal Dose of Omeprazole After Endoscopic Treatment of Bleeding Peptic Ulcers
- First Posted Date
- 2007-08-22
- Last Posted Date
- 2017-02-10
- Lead Sponsor
- Singapore General Hospital
- Target Recruit Count
- 126
- Registration Number
- NCT00519519
- Locations
- 🇸🇬
Department of Surgery, Singapore General Hospital, Singapore, Outram road, Singapore
🇸🇬Singapore General Hospital, Singapore, Outram Road, Singapore
Effect of a Proton Pump Inhibitor on Gleevec® in Healthy Volunteers
- First Posted Date
- 2007-03-12
- Last Posted Date
- 2016-06-22
- Lead Sponsor
- University of Pittsburgh
- Target Recruit Count
- 15
- Registration Number
- NCT00446004
- Locations
- 🇺🇸
University of Pittsburgh Cancer Institute / Clinical and Translational Research Center (Hillman Cancer Center and Montefiore University Hospital locations), Pittsburgh, Pennsylvania, United States
A Parallel Group Study to Compare the Gastroprotective Effects of PA 325 Versus 81 mg Enteric Coated Aspirin
- Conditions
- First Posted Date
- 2007-03-01
- Last Posted Date
- 2009-01-12
- Lead Sponsor
- POZEN
- Target Recruit Count
- 80
- Registration Number
- NCT00441519
- Locations
- 🇺🇸
POZEN, Chapel Hill, North Carolina, United States
🇨🇦MDS Pharma Services, Montreal, Quebec, Canada
To Compare the Gastroprotective Effects and Pharmacokinetic Profile of PA Versus Enteric-Coated Aspirin
- Conditions
- First Posted Date
- 2007-03-01
- Last Posted Date
- 2007-03-01
- Lead Sponsor
- POZEN
- Target Recruit Count
- 80
- Registration Number
- NCT00442052
- Locations
- 🇨🇦
MDS Pharma Services, Montreal, Quebec, Canada
🇺🇸POZEN, Chapel Hill, North Carolina, United States
High Versus Standard Dose of Proton Pump Inhibitors (PPIs) in Peptic Ulcer Bleeding
- Conditions
- First Posted Date
- 2006-09-08
- Last Posted Date
- 2007-04-05
- Lead Sponsor
- Casa Sollievo della Sofferenza IRCCS
- Target Recruit Count
- 450
- Registration Number
- NCT00374101
- Locations
- 🇮🇹
Division of Internal Medicine, Polla, Salerno, Italy
🇮🇹Division of Gastroenterology, Vasto, Italy
🇮🇹DIvision of Gastroenterology, Como, Italy
Tongue Exercises and Reflux Therapy for Upper Airway Resistance Syndrome
- Conditions
- First Posted Date
- 2006-08-15
- Last Posted Date
- 2012-12-20
- Lead Sponsor
- West Side ENT
- Registration Number
- NCT00364481
Corticosteroids to Reduce Frequency of Seizures in Neurocysticercosis Patients
- Conditions
- Interventions
- First Posted Date
- 2006-02-13
- Last Posted Date
- 2017-02-03
- Target Recruit Count
- 110
- Registration Number
- NCT00290823
- Locations
- 🇵🇪
Instituto Especializado en Ciencias Neurologicas, Lima, Peru
Healing Effects of Rebamipide and Omeprazole in Helicobacter Pylori-positive Gastric Ulcer After Eradication Therapy
- First Posted Date
- 2006-01-06
- Last Posted Date
- 2015-04-29
- Lead Sponsor
- Korea Otsuka International Asia Arab
- Target Recruit Count
- 132
- Registration Number
- NCT00272467
- Locations
- 🇰🇷
Korea University Ansan Hospital, Ansan, Korea, Republic of
🇰🇷Severance Hospital, Seoul National University, Seoul, Korea, Republic of
🇨🇳The 1st Affiliated hospital - Zhongshan Univ., Guangzhou, Guangdong, China
Four-week Omeprazole Treatment of Non-erosive Reflux Disease in a Japanese Population
- Conditions
- First Posted Date
- 2005-11-29
- Last Posted Date
- 2011-01-24
- Lead Sponsor
- AstraZeneca
- Target Recruit Count
- 270
- Registration Number
- NCT00259077
Drug Development Updates
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