Pentamidine

Generic Name
Pentamidine
Brand Names
Nebupent, Pentam
Drug Type
Small Molecule
Chemical Formula
C19H24N4O2
CAS Number
100-33-4
Unique Ingredient Identifier
673LC5J4LQ
Background

Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of pneumocystis pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.

Indication

For the treatment of pneumonia due to Pneumocystis carinii.

Associated Conditions
Pneumocystis Jirovecii Pneumonia, Trypanosomiasis
Associated Therapies
-

A Controlled Trial Comparing the Efficacy of Aerosolized Pentamidine and Parenteral/Oral Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia in AIDS

First Posted Date
2001-08-31
Last Posted Date
2021-11-03
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
240
Registration Number
NCT00000715
Locations
🇺🇸

Harvard (Massachusetts Gen Hosp), Boston, Massachusetts, United States

🇺🇸

Julio Arroyo, West Columbia, South Carolina, United States

🇺🇸

Bronx Municipal Hosp Ctr/Jacobi Med Ctr, Bronx, New York, United States

and more 6 locations

A Study of Two Forms of Pentamidine in HIV-Infected Children Who May Have Pneumocystis Carinii Pneumonia

First Posted Date
2001-08-31
Last Posted Date
2021-11-01
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
16
Registration Number
NCT00000974
Locations
🇺🇸

UCLA-Los Angeles/Brazil AIDS Consortium (LABAC) CRS, Los Angeles, California, United States

🇺🇸

Childrens Hosp. LA - Dept. of Ped., Div. of Clinical Immunology & Allergy, Los Angeles, California, United States

🇺🇸

Children's Hosp. & Research Ctr. Oakland, Ped. Clinical Research Ctr. & Research Lab., Oakland, California, United States

and more 1 locations
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