Simethicone
- Generic Name
- Simethicone
- Brand Names
- Phazyme
- Drug Type
- Small Molecule
- Chemical Formula
- C6H18O4Si3
- CAS Number
- 8050-81-5
- Unique Ingredient Identifier
- -
- Background
Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas bubbles to facilitate their elimination. It has a favourable safety profile as it is not systemically absorbed.
Simethicone has been in use since the 1940s but was granted FDA approval in 1952.
- Indication
Simethicone is indicated for the treatment of bloating, pressure, and cramps caused by gas. Simethicone is also used as part of bowel preparation for colonoscopies.
- Associated Conditions
- Abdominal Cramping, Abdominal Pain, Bloating, Colic, Diarrhea, Distension, Distention, Dyspepsia, Flatulence, Gastric Ulcer, Gastritis, Heartburn, Hiatus Hernia, Hyperacidity, Pain, Pancreatic Insufficiency, Peptic Esophagitis, Peptic Ulcer, Reflux Acid, Stomach ache, Gastrointestinal cramping, Gastrointestinal cramps caused by Gas, Gastrointestinal spasms, Stomach cramps
- Associated Therapies
- Antacid therapy, Bowel preparation therapy
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